SCOPe 2.07: Domain d2zo2b2: 2zo2 B:419-625

Lineage for d2zo2b2 (2zo2 B:419-625)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.122: PUA domain-like [88696] (1 superfamily)
   pseudobarrel; mixed folded sheet of 5 strands; order 13452; strand 1 and 3 are parallel to each other

4. Superfamily b.122.1: PUA domain-like [88697] (14 families)

5. Family b.122.1.12: SRA domain-like [159368] (2 proteins)
   Pfam PF02182; recognizes the modified cytosine base (m5C) by flipping it out of DNA

6. Protein E3 ubiquitin-protein ligase UHRF1 [159369] (2 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [159371] (10 PDB entries)
   Uniprot Q8VDF2 405-613! Uniprot Q8VDF2 418-625

8. Domain d2zo2b2: 2zo2 B:419-625 [154713]
   Other proteins in same PDB: d2zo2b3
   automated match to d3fdea_
   protein/DNA complex; complexed with po4

Details for d2zo2b2

PDB Entry: 2zo2, 3.09 Å

PDB Description: Mouse NP95 SRA domain non-specific DNA complex

PDB Compounds: (B:) E3 ubiquitin-protein ligase UHRF1

SCOPe Domain Sequences for d2zo2b2:

Sequence, based on SEQRES records:

>d2zo2b2 b.122.1.12 (B:419-625) E3 ubiquitin-protein ligase UHRF1 {Mouse (Mus musculus) [TaxId: 10090]}
panhfgpipgvpvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdng
nyftytgsggrdlsgnkrtagqssdqkltnnnralalnchspinekgaeaedwrqgkpvr
vvrnmkggkhskyapaegnrydgiykvvkywpergksgflvwryllrrddtepepwtreg
kdrtrqlgltmqypegylealankeks

Sequence, based on observed residues (ATOM records):

>d2zo2b2 b.122.1.12 (B:419-625) E3 ubiquitin-protein ligase UHRF1 {Mouse (Mus musculus) [TaxId: 10090]}
panhfgpipgvpvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdng
nyftytgsggrdgqssdqkltnnnralalnchspinekgaeaedwrqgkpvrvvrnmkgg
khskyapaegnrydgiykvvkywpergksgflvwryllrrddtepepwtregkdrtrqlg
ltmqypegylealankeks

Timeline for d2zo2b2:

• d2zo2b2 first appeared in SCOP 1.75, called d2zo2b1
  
• d2zo2b2 appears in SCOPe 2.06
  
• d2zo2b2 appears in the current release, SCOPe 2.08