SCOPe 2.07: Domain d2ytza_: 2ytz A:

Lineage for d2ytza_ (2ytz A:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families)

5. Family c.66.1.58: TRM1-like [159697] (1 protein)
   Pfam PF02005; contains extra C-terminal alpha+beta subdomain

6. Protein N(2),N(2)-dimethylguanosine tRNA methyltransferase Trm1 [159698] (1 species)

7. Species Pyrococcus horikoshii [TaxId:53953] [159699] (4 PDB entries)
   Uniprot O59493 3-377

8. Domain d2ytza_: 2ytz A: [153776]
   automated match to d2dula1
   protein/RNA complex; complexed with sah, so4

Details for d2ytza_

PDB Entry: 2ytz, 2.65 Å

PDB Description: Complex structure of Trm1 from Pyrococcus horikoshii with S-adenosyl-L-Homocystein in the orthorhombic crystal-lattice

PDB Compounds: (A:) N(2),N(2)-dimethylguanosine tRNA methyltransferase

SCOPe Domain Sequences for d2ytza_:

Sequence, based on SEQRES records:

>d2ytza_ c.66.1.58 (A:) N(2),N(2)-dimethylguanosine tRNA methyltransferase Trm1 {Pyrococcus horikoshii [TaxId: 53953]}
elievqegkakilipkaesiydspvfynprmalnrdivvvllnilnpkivldalsatgir
girfaletpaeevwlndisedayelmkrnvmlnfdgelreskgrailkgektivinhdda
nrlmaerhryfhfidldpfgspmefldtalrsakrrgilgvtatdgaplcgahpraclrk
ylavplrgelchevgtrilvgviaryaakydlgidvilayykdhyfrafvklkdgarkgd
etleklgyiyfddktgkfeleqgflptrpnaygpvwlgplkdekivskmvkeaeslslar
kkqalkllkmidqeldiplfydthaigrrlkietkkveeiisalreqgyeatrthfsptg
iktsapyevfietikr

Sequence, based on observed residues (ATOM records):

>d2ytza_ c.66.1.58 (A:) N(2),N(2)-dimethylguanosine tRNA methyltransferase Trm1 {Pyrococcus horikoshii [TaxId: 53953]}
elievqegkakilipkaesiydspvfynprmalnrdivvvllnilnpkivldalsatgir
girfaletpaeevwlndisedayelmkrnvmlnfdgelreskgrailkgektivinhdda
nrlmaerhryfhfidldpfgspmefldtalrsakrrgilgvtatdgaplcgahpraclrk
ylavplrgelchevgtrilvgviaryaakydlgidvilayykdhyfrafvklkdgarkgd
etleklgyiyfddktgkfeleqgflptrpnaygpvwlgplkdekivskmvkeaeslslar
kkqalkllkmidqeldiplfydthaigrrkkveeiisalreqgyeatrthfsptgiktsa
pyevfietikr

Timeline for d2ytza_:

• d2ytza_ first appeared in SCOP 1.75, called d2ytza1
  
• d2ytza_ appears in SCOPe 2.06
  
• d2ytza_ appears in the current release, SCOPe 2.08