SCOPe 2.07: Domain d2r8kb2: 2r8k B:1-389

Lineage for d2r8kb2 (2r8k B:1-389)

1. Root: SCOPe 2.07

2. Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.7: Lesion bypass DNA polymerase (Y-family), catalytic domain [100888] (5 proteins)
   contains a distinct 'fingers' domain possibly related to the C-terminal subdomain of hypothetical protein Ta1206 (1qw2)

6. Protein DNA polymerase eta [100892] (1 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [100893] (3 PDB entries)

8. Domain d2r8kb2: 2r8k B:1-389 [151730]
   Other proteins in same PDB: d2r8ka1, d2r8ka3, d2r8kb1, d2r8kb3
   automatically matched to d1jiha2
   protein/DNA complex; complexed with ca, cpt, dtp

Details for d2r8kb2

PDB Entry: 2r8k, 3.3 Å

PDB Description: Structure of the Eukaryotic DNA Polymerase eta in complex with 1,2-d(GpG)-cisplatin containing DNA

PDB Compounds: (B:) DNA Polymerase ETA

SCOPe Domain Sequences for d2r8kb2:

Sequence; same for both SEQRES and ATOM records:

>d2r8kb2 e.8.1.7 (B:1-389) DNA polymerase eta {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
mskftwkeliqlgspskayesslaciahidmnaffaqveqmrcglskedpvvcvqwnsii
avsyaarkygisrmdtiqealkkcsnlipihtavfkkgedfwqyhdgcgswvqdpakqis
vedhkvslepyrresrkalkifksacdlverasidevfldlgricfnmlmfdneyeltgd
lklkdalsnireafiggnydinshlplipekikslkfegdvfnpegrdlitdwddvilal
gsqvckgirdsikdilgyttscglsstknvcklasnykkpdaqtivkndclldfldcgkf
eitsfwtlggvlgkelidvldlphensikhiretwpdnagqlkefldakvkqsdydrsts
nidplktadlaeklfklsrgryglplssr

Timeline for d2r8kb2:

• d2r8kb2 first appeared in SCOP 1.75
  
• d2r8kb2 appears in SCOPe 2.06
  
• d2r8kb2 appears in the current release, SCOPe 2.08