SCOPe 2.07: Domain d2qnva_: 2qnv A:

Lineage for d2qnva_ (2qnv A:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Pregnane x receptor, PXR [63624] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63625] (31 PDB entries)

8. Domain d2qnva_: 2qnv A: [150955]
   automated match to d1m13a_
   protein/DNA complex; complexed with cdz

Details for d2qnva_

PDB Entry: 2qnv, 2.8 Å

PDB Description: crystal structure of the pregnane x receptor bound to colupulone

PDB Compounds: (A:) orphan nuclear receptor pxr

SCOPe Domain Sequences for d2qnva_:

Sequence, based on SEQRES records:

>d2qnva_ a.123.1.1 (A:) Pregnane x receptor, PXR {Human (Homo sapiens) [TaxId: 9606]}
glteeqrmmirelmdaqmktfdttfshfknfrlpgvlssgcelpeslqapsreeaakwsq
vrkdlcslkvslqlrgedgsvwnykppadsggkeifsllphmadmstymfkgiisfakvi
syfrdlpiedqisllkgaafelcqlrfntvfnaetgtwecgrlsycledtaggfqqllle
pmlkfhymlkklqlheeeyvlmqaislfspdrpgvlqhrvvdqlqeqfaitlksyiecnr
pqpahrflflkimamltelrsinaqhtqrllriqdihpfatplmqelfgitgs

Sequence, based on observed residues (ATOM records):

>d2qnva_ a.123.1.1 (A:) Pregnane x receptor, PXR {Human (Homo sapiens) [TaxId: 9606]}
glteeqrmmirelmdaqmktfdttfshfknfrlpgvlkvslqlrgedgsvwnykppafsl
lphmadmstymfkgiisfakvisyfrdlpiedqisllkgaafelcqlrfntvfnaetgtw
ecgrlsycleqqlllepmlkfhymlkklqlheeeyvlmqaislfspdrpgvlqhrvvdql
qeqfaitlksyiecnrpqpahrflflkimamltelrsinaqhtqrllriqdihpfatplm
qelfgitgs

Timeline for d2qnva_:

• d2qnva_ first appeared in SCOP 1.75, called d2qnva1
  
• d2qnva_ appears in SCOPe 2.06
  
• d2qnva_ appears in the current release, SCOPe 2.08