Lineage for d2v0ma1 (2v0m A:30-498)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2336229Fold a.104: Cytochrome P450 [48263] (1 superfamily)
    multihelical
  4. 2336230Superfamily a.104.1: Cytochrome P450 [48264] (2 families) (S)
  5. 2336231Family a.104.1.1: Cytochrome P450 [48265] (23 proteins)
  6. 2336849Protein Mammalian cytochrome P450 3a4 [109958] (1 species)
  7. 2336850Species Human (Homo sapiens) [TaxId:9606] [109959] (7 PDB entries)
    Uniprot P08684
  8. 2336853Domain d2v0ma1: 2v0m A:30-498 [140050]
    complexed with hem, kln

Details for d2v0ma1

PDB Entry: 2v0m (more details), 2.8 Å

PDB Description: crystal structure of human p450 3a4 in complex with ketoconazole
PDB Compounds: (A:) cytochrome p450 3a4

SCOPe Domain Sequences for d2v0ma1:

Sequence, based on SEQRES records: (download)

>d2v0ma1 a.104.1.1 (A:30-498) Mammalian cytochrome P450 3a4 {Human (Homo sapiens) [TaxId: 9606]}
hglfkklgipgptplpflgnilsyhkgfcmfdmechkkygkvwgfydgqqpvlaitdpdm
iktvlvkecysvftnrrpfgpvgfmksaisiaedeewkrlrsllsptftsgklkemvpii
aqygdvlvrnlrreaetgkpvtlkdvfgaysmdvitstsfgvnidslnnpqdpfventkk
llrfdfldpfflsitvfpflipilevlnicvfprevtnflrksvkrmkesrledtqkhrv
dflqlmidsqnsketeshkalsdlelvaqsiififagyettssvlsfimyelathpdvqq
klqeeidavlpnkapptydtvlqmeyldmvvnetlrlfpiamrlervckkdveingmfip
kgvvvmipsyalhrdpkywtepekflperfskknkdnidpyiytpfgsgprncigmrfal
mnmklalirvlqnfsfkpcketqiplklslggllqpekpvvlkvesrdg

Sequence, based on observed residues (ATOM records): (download)

>d2v0ma1 a.104.1.1 (A:30-498) Mammalian cytochrome P450 3a4 {Human (Homo sapiens) [TaxId: 9606]}
hglfkklgipgptplpflgnilsyhkgfcmfdmechkkygkvwgfydgqqpvlaitdpdm
iktvlvkecysvftnrrpfgpvgfmksaisiaedeewkrlrsllsptftsgklkemvpii
aqygdvlvrnlrreaetgkpvtlkdvfgaysmdvitstsfgvnidslnnpqdpfventkk
llrfdfldpfflsitvfpflipilevlnicvfprevtnflrksvkrmkesrledvdflql
midsqalsdlelvaqsiififagyettssvlsfimyelathpdvqqklqeeidavlpnka
pptydtvlqmeyldmvvnetlrlfpiamrlervckkdveingmfipkgvvvmipsyalhr
dpkywtepekflperfskknkdnidpyiytpfgsgprncigmrfalmnmklalirvlqnf
sfkpcketqiplklslggllqpekpvvlkvesrdg

SCOPe Domain Coordinates for d2v0ma1:

Click to download the PDB-style file with coordinates for d2v0ma1.
(The format of our PDB-style files is described here.)

Timeline for d2v0ma1: