SCOPe 2.04: Domain d2nppd1: 2npp D:9-589

Lineage for d2nppd1 (2npp D:9-589)

1. Root: SCOPe 2.04

2. Class a: All alpha proteins [46456] (285 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (24 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.1: ARM repeat [48371] (26 families)

5. Family a.118.1.2: HEAT repeat [48385] (2 proteins)
   Pfam PF02985
   this is a repeat family; one repeat unit is 1b3u A:295-335 found in domain

6. Protein Constant regulatory domain of protein phosphatase 2a, pr65alpha [48386] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48387] (12 PDB entries)

8. Domain d2nppd1: 2npp D:9-589 [138446]
   Other proteins in same PDB: d2nppb1, d2nppc1, d2nppe1, d2nppf1
   automatically matched to d1b3ua_
   complexed with mn

Details for d2nppd1

PDB Entry: 2npp, 3.3 Å

PDB Description: Structure of the Protein Phosphatase 2A Holoenzyme

PDB Compounds: (D:) Protein Phosphatase 2, regulatory subunit A (PR 65), alpha isoform

SCOPe Domain Sequences for d2nppd1:

Sequence; same for both SEQRES and ATOM records:

>d2nppd1 a.118.1.2 (D:9-589) Constant regulatory domain of protein phosphatase 2a, pr65alpha {Human (Homo sapiens) [TaxId: 9606]}
slypiavlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiydedevlla
laeqlgtfttlvggpeyvhcllppleslatveetvvrdkaveslraishehspsdleahf
vplvkrlaggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpmvrraaask
lgefakvleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedlealvmptl
rqaaedkswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevraaashkvke
fcenlsadcrenvimsqilpcikelvsdanqhvksalasvimglspilgkdntiehllpl
flaqlkdecpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvrlaiieymp
llagqlgveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewahatiipkvla
msgdpnylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnvakslqkig
pildnstlqsevkpilekltqdqdvdvkyfaqealtvlsla

Timeline for d2nppd1:

• d2nppd1 first appeared in SCOP 1.73
  
• d2nppd1 appears in SCOPe 2.03
  
• d2nppd1 appears in SCOPe 2.05
  
• d2nppd1 appears in the current release, SCOPe 2.08