SCOP 1.75: Domain d2nppa1: 2npp A:9-589

Lineage for d2nppa1 (2npp A:9-589)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (24 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.1: ARM repeat [48371] (23 families)

5. Family a.118.1.2: HEAT repeat [48385] (2 proteins)
   Pfam PF02985
   this is a repeat family; one repeat unit is 1b3u A:295-335 found in domain

6. Protein Constant regulatory domain of protein phosphatase 2a, pr65alpha [48386] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48387] (8 PDB entries)

8. Domain d2nppa1: 2npp A:9-589 [138444]
   Other proteins in same PDB: d2nppb1, d2nppc1, d2nppe1, d2nppf1
   automatically matched to d1b3ua_
   complexed with acb, add, cab, mn

Details for d2nppa1

PDB Entry: 2npp, 3.3 Å

PDB Description: Structure of the Protein Phosphatase 2A Holoenzyme

PDB Compounds: (A:) Protein Phosphatase 2, regulatory subunit A (PR 65), alpha isoform

SCOP Domain Sequences for d2nppa1:

Sequence; same for both SEQRES and ATOM records:

>d2nppa1 a.118.1.2 (A:9-589) Constant regulatory domain of protein phosphatase 2a, pr65alpha {Human (Homo sapiens) [TaxId: 9606]}
slypiavlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiydedevlla
laeqlgtfttlvggpeyvhcllppleslatveetvvrdkaveslraishehspsdleahf
vplvkrlaggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpmvrraaask
lgefakvleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedlealvmptl
rqaaedkswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevraaashkvke
fcenlsadcrenvimsqilpcikelvsdanqhvksalasvimglspilgkdntiehllpl
flaqlkdecpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvrlaiieymp
llagqlgveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewahatiipkvla
msgdpnylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnvakslqkig
pildnstlqsevkpilekltqdqdvdvkyfaqealtvlsla

Timeline for d2nppa1:

• d2nppa1 first appeared in SCOP 1.73
  
• d2nppa1 appears in SCOPe 2.01
  
• d2nppa1 appears in the current release, SCOPe 2.08