SCOPe 2.08: Domain d2ieja_: 2iej A:

Lineage for d2ieja_ (2iej A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.6: Protein prenylyltransferase [48439] (2 families)

5. Family a.118.6.1: Protein prenylyltransferase [48440] (3 proteins)

6. Protein Protein farnesyltransferase alpha-subunit [48441] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69093] (13 PDB entries)
   Uniprot P49354

8. Domain d2ieja_: 2iej A: [137313]
   Other proteins in same PDB: d2iejb_
   automated match to d1tn6a_
   complexed with act, fii, s48, zn

Details for d2ieja_

PDB Entry: 2iej, 1.8 Å

PDB Description: human protein farnesyltransferase complexed with inhibitor compound stn-48 and fpp analog at 1.8a resolution

PDB Compounds: (A:) Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit

SCOPe Domain Sequences for d2ieja_:

Sequence; same for both SEQRES and ATOM records:

>d2ieja_ a.118.6.1 (A:) Protein farnesyltransferase alpha-subunit {Human (Homo sapiens) [TaxId: 9606]}
fvsldspsyvlyrdraewadidpvpqndgpnpvvqiiysdkfrdvydyfravlqrderse
rafkltrdaielnaanytvwhfrrvllkslqkdlheemnyitaiieeqpknyqvwhhrrv
lvewlrdpsqelefiadilnqdaknyhawqhrqwviqefklwdnelqyvdqllkedvrnn
svwnqryfvisnttgyndravlerevqytlemiklvphnesawnylkgilqdrglskypn
llnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirke
ywryigrslqskhst

Timeline for d2ieja_:

• d2ieja_ first appeared in SCOP 1.73, called d2ieja1
  
• d2ieja_ appears in SCOPe 2.07