SCOPe 2.08: Domain d2i5yg2: 2i5y G:83-492

Lineage for d2i5yg2 (2i5y G:83-492)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.172: gp120 core [56501] (1 superfamily)
   unusual fold

4. Superfamily d.172.1: gp120 core [56502] (1 family)

5. Family d.172.1.1: gp120 core [56503] (2 proteins)

6. Protein gp120 core [56504] (3 species)

7. Species Human immunodeficiency virus [TaxId:12721] [190021] (1 PDB entry)

8. Domain d2i5yg2: 2i5y G:83-492 [137071]
   Other proteins in same PDB: d2i5yg3, d2i5yh1, d2i5yh2, d2i5yl1, d2i5yl2, d2i5ym1, d2i5yp3, d2i5yq1, d2i5yq2, d2i5yr1, d2i5yr2, d2i5ys1
   automated match to d1g9ng_
   complexed with nag

Details for d2i5yg2

PDB Entry: 2i5y, 2.2 Å

PDB Description: crystal structure of cd4m47, a scorpion-toxin mimic of cd4, in complex with hiv-1 yu2 gp120 envelope glycoprotein and anti-hiv-1 antibody 17b

PDB Compounds: (G:) Exterior membrane glycoprotein(GP120)

SCOPe Domain Sequences for d2i5yg2:

Sequence, based on SEQRES records:

>d2i5yg2 d.172.1.1 (G:83-492) gp120 core {Human immunodeficiency virus [TaxId: 12721]}
evklenvtenfnmwknnmveqmhediislwdqslkpcvkltplcvgagscntsvitqacp
kvsfepipihycapagfailkcndkkfngtgpctnvstvqcthgirpvvstqlllngsla
eeeivirsenftnnaktiivqlnesvvinctgaghcnlsktqwentleqiaiklkeqfgn
nktiifnpssggdpeivthsfncggeffycnstqlftwndtrklnntgrnitlpcrikqi
inmwqevgkamyappirgqircssnitgllltrdggkdtngteifrpgggdmrdnwrsel
ykykvvkie

Sequence, based on observed residues (ATOM records):

>d2i5yg2 d.172.1.1 (G:83-492) gp120 core {Human immunodeficiency virus [TaxId: 12721]}
evklenvtenfnmwknnmveqmhediislwdqslkpcvkltplcvgagscntsvitqacp
kvsfepipihycapagfailkcndkkfngtgpctnvstvqcthgirpvvstqlllngsla
eeeivirsenftnnaktiivqlnesvvinctgaghcnlsktqwentleqiaiklkeqfgn
nktiifnpssggdpeivthsfncggeffycnstqlftwndrnitlpcrikqiinmwqevg
kamyappirgqircssnitgllltrdggkdtngteifrpgggdmrdnwrselykykvvki
e

Timeline for d2i5yg2:

• d2i5yg2 first appeared in SCOP 1.73, called d2i5yg1
  
• d2i5yg2 appears in SCOPe 2.07