Lineage for d2i4zb_ (2i4z B:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2008476Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 2008477Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families) (S)
  5. 2008478Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 protein domains)
  6. 2008960Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)
  7. 2008961Species Human (Homo sapiens) [TaxId:9606] [48525] (104 PDB entries)
    Uniprot P37231 232-505
  8. 2009044Domain d2i4zb_: 2i4z B: [137054]
    automated match to d1nyxa_
    complexed with drh

Details for d2i4zb_

PDB Entry: 2i4z (more details), 2.25 Å

PDB Description: Crystal structure of the complex between PPARgamma and the partial agonist LT127 (ureidofibrate derivative). This structure has been obtained from crystals soaked for 6 hours.
PDB Compounds: (B:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d2i4zb_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2i4zb_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2i4zb_:

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Timeline for d2i4zb_: