SCOPe 2.08: Domain d2hhna_: 2hhn A:

Lineage for d2hhna_ (2hhn A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.1: Papain-like [54002] (26 proteins)

6. Protein (Pro)cathepsin S [82566] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82567] (28 PDB entries)

8. Domain d2hhna_: 2hhn A: [136501]
   automated match to d1ms6a_
   complexed with gnq, so4

Details for d2hhna_

PDB Entry: 2hhn, 1.55 Å

PDB Description: cathepsin s in complex with non covalent arylaminoethyl amide.

PDB Compounds: (A:) cathepsin S

SCOPe Domain Sequences for d2hhna_:

Sequence; same for both SEQRES and ATOM records:

>d2hhna_ d.3.1.1 (A:) (Pro)cathepsin S {Human (Homo sapiens) [TaxId: 9606]}
nrilpdsvdwrekgcvtevkyqgscgacwafsavgaleaqlklktgklvslsaqnlvdcs
tekygnkgcnggfmttafqyiidnkgidsdasypykamdqkcqydskyraatcskytelp
ygredvlkeavankgpvsvgvdarhpsfflyrsgvyyepsctqnvnhgvlvvgygdlngk
eywlvknswghnfgeegyirmarnkgnhcgiasfpsypei

Timeline for d2hhna_:

• d2hhna_ first appeared in SCOP 1.73, called d2hhna1
  
• d2hhna_ appears in SCOPe 2.07