SCOPe 2.06: Domain d2fmea_: 2fme A:

Lineage for d2fmea_ (2fme A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.9: Motor proteins [52641] (5 proteins)

6. Protein automated matches [190129] (6 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187145] (33 PDB entries)

8. Domain d2fmea_: 2fme A: [133771]
   automated match to d1q0bb_
   complexed with 3qc, adp, mg

Details for d2fmea_

PDB Entry: 2fme, 2.1 Å

PDB Description: crystal structure of the mitotic kinesin eg5 (ksp) in complex with mg- adp and (r)-4-(3-hydroxyphenyl)-n,n,7,8-tetramethyl-3,4- dihydroisoquinoline-2(1h)-carboxamide

PDB Compounds: (A:) Kinesin-like protein KIF11

SCOPe Domain Sequences for d2fmea_:

Sequence, based on SEQRES records:

>d2fmea_ c.37.1.9 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgast
kqidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagii
prtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgvii
kgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeelv
kigklnlvdlagsenigrsgavdkrareagninqslltlgrvitalvertphvpyreskl
trilqdslggrtrtsiiatispaslnleetlstleyahraknilnkp

Sequence, based on observed residues (ATOM records):

>d2fmea_ c.37.1.9 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggssrktytfdmvfgastkqid
vyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiiprtl
hqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviikgle
eitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkvkigklnlvdlags
enigrinqslltlgrvitalvertphvpyreskltrilqdslggrtrtsiiatispasln
leetlstleyahraknilnkp

Timeline for d2fmea_:

• d2fmea_ first appeared in SCOP 1.73, called d2fmea1
  
• d2fmea_ appears in SCOPe 2.05
  
• d2fmea_ appears in SCOPe 2.07
  
• d2fmea_ appears in the current release, SCOPe 2.08