SCOPe 2.07: Domain d2exaa_: 2exa A:

Lineage for d2exaa_ (2exa A:)

1. Root: SCOPe 2.07

2. Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)

3. Fold e.3: beta-lactamase/transpeptidase-like [56600] (1 superfamily)
   contains a cluster of helices and an alpha+beta sandwich

4. Superfamily e.3.1: beta-lactamase/transpeptidase-like [56601] (4 families)

5. Family e.3.1.3: Dac-like [144040] (3 proteins)
   Pfam PF02113; D-Ala-D-Ala carboxypeptidase 3 (S13) family; contains a large insertion comprising two subdomains: (d1) aplha+beta with topological similarity to one subunit of the DTD-like family (69501) and (d2) six-stranded beta-sandwich with a crossed-loop topology

6. Protein DD-carboxypeptidase DacB [144045] (2 species)
   Penicillin-binding protein 4

7. Species Escherichia coli [TaxId:562] [144046] (6 PDB entries)
   Uniprot P24228 22-477

8. Domain d2exaa_: 2exa A: [132521]
   automated match to d2ex2a1
   complexed with dgf, gol

Details for d2exaa_

PDB Entry: 2exa, 1.7 Å

PDB Description: crystal structure of penicillin binding protein 4 (dacb) from escherichia coli, complexed with farom

PDB Compounds: (A:) Penicillin-binding protein 4

SCOPe Domain Sequences for d2exaa_:

Sequence, based on SEQRES records:

>d2exaa_ e.3.1.3 (A:) DD-carboxypeptidase DacB {Escherichia coli [TaxId: 562]}
yitqlpaganlalmvqkvgasapaidyhsqqmalpastqkvitalaaliqlgpdfrfttt
letkgnvengvlkgdlvarfgadptlkrqdirnmvatlkksgvnqidgnvlidtsifash
dkapgwpwndmtqcfsappaaaivdrncfsvslysapkpgdmafirvasyypvtmfsqvr
tlprgsaeaqyceldvvpgdlnrftltgclpqrseplplafavqdgasyagailkyelkq
agitwsgtllrqtqvnepgtvvaskqsaplhdllkimlkksdnmiadtvfrmigharfnv
pgtwragsdavrqilrqqagvdigntiiadgsglsrhnliapatmmqvlqyiaqhdneln
fismlplagydgslqyraglhqagvdgkvsaktgslqgvynlagfittasgqrmafvqyl
sgyavepadqrnrriplvrfesrlykdiyqnn

Sequence, based on observed residues (ATOM records):

>d2exaa_ e.3.1.3 (A:) DD-carboxypeptidase DacB {Escherichia coli [TaxId: 562]}
yitqlpaganlalmvqkvgasapaidyhsqqmalpastqkvitalaaliqlgpdfrfttt
letkgnvengvlkgdlvarfgadptlkrqdirnmvatlkksgvnqidgnvlidtsifash
dkapgwpwndmtqcfsappaaaivdrncfsvslysapkpgdmafirvasyypvtmfsqvr
tlprgsaeaqyceldvvpgdlnrftltgclpqrseplplafavqdgasyagailkyelkq
agitwsgtllrqtqvnepgtvvaskqsaplhdllkimlkksdnmiadtvfrmigharfnv
pgtwragsdavrqilrqqagvdigntiiadgsglsrhnliapatmmqvlqyiaqhdneln
fismlplagydgslqyraglhqagvdgkvsaktgslqgvynlagfittasgqrmafvqyl
sgyariplvrfesrlykdiyqnn

Timeline for d2exaa_:

• d2exaa_ first appeared in SCOP 1.73, called d2exaa1
  
• d2exaa_ appears in SCOPe 2.06
  
• d2exaa_ appears in the current release, SCOPe 2.08