PDB entry 2exa

View 2exa on RCSB PDB site
Description: Crystal structure of penicillin binding protein 4 (dacB) from Escherichia coli, complexed with FAROM
Class: hydrolase
Keywords: penicillin-binding protein, penicillin,cephem, penem, FAROM, D-alanyl-D-alanine-carboxypeptidase, D-alanyl-D-alanine-endopeptidase, hydrolase
Deposited on 2005-11-08, released 2006-06-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-10-19, with a file datestamp of 2016-10-14.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Penicillin-binding protein 4
    Species: Escherichia coli [TaxId:562]
    Gene: dacb
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24228 (Start-457)
      • engineered mutation (241)
    Domains in SCOPe 2.07: d2exaa_
  • Heterogens: DGF, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2exaA (A:)
manvdeyitqlpaganlalmvqkvgasapaidyhsqqmalpastqkvitalaaliqlgpd
frftttletkgnvengvlkgdlvarfgadptlkrqdirnmvatlkksgvnqidgnvlidt
sifashdkapgwpwndmtqcfsappaaaivdrncfsvslysapkpgdmafirvasyypvt
mfsqvrtlprgsaeaqyceldvvpgdlnrftltgclpqrseplplafavqdgasyagail
kyelkqagitwsgtllrqtqvnepgtvvaskqsaplhdllkimlkksdnmiadtvfrmig
harfnvpgtwragsdavrqilrqqagvdigntiiadgsglsrhnliapatmmqvlqyiaq
hdnelnfismlplagydgslqyraglhqagvdgkvsaktgslqgvynlagfittasgqrm
afvqylsgyavepadqrnrriplvrfesrlykdiyqnn

    Sequence, based on observed residues (ATOM records): (download) 
    >2exaA (A:)
yitqlpaganlalmvqkvgasapaidyhsqqmalpastqkvitalaaliqlgpdfrfttt
letkgnvengvlkgdlvarfgadptlkrqdirnmvatlkksgvnqidgnvlidtsifash
dkapgwpwndmtqcfsappaaaivdrncfsvslysapkpgdmafirvasyypvtmfsqvr
tlprgsaeaqyceldvvpgdlnrftltgclpqrseplplafavqdgasyagailkyelkq
agitwsgtllrqtqvnepgtvvaskqsaplhdllkimlkksdnmiadtvfrmigharfnv
pgtwragsdavrqilrqqagvdigntiiadgsglsrhnliapatmmqvlqyiaqhdneln
fismlplagydgslqyraglhqagvdgkvsaktgslqgvynlagfittasgqrmafvqyl
sgyariplvrfesrlykdiyqnn