SCOP 1.75: Domain d2cfia2: 2cfi A:1-203

Lineage for d2cfia2 (2cfi A:1-203)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.65: Formyltransferase [53327] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 7 strands, order 3214567; strand 6 is antiparallel to the rest

4. Superfamily c.65.1: Formyltransferase [53328] (1 family)

5. Family c.65.1.1: Formyltransferase [53329] (4 proteins)

6. Protein 10-formyltetrahydrofolate dehydrogenase domain 1 [102552] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [142568] (2 PDB entries)
   Uniprot O75891 1-203

8. Domain d2cfia2: 2cfi A:1-203 [130383]
   Other proteins in same PDB: d2cfia1
   automatically matched to 2BW0 A:1-203
   complexed with so4, zzz

Details for d2cfia2

PDB Entry: 2cfi, 1.85 Å

PDB Description: the hydrolase domain of human 10-fthfd in complex with 6-formyltetrahydropterin

PDB Compounds: (A:) 10-formyltetrahydrofolate dehydrogenase

SCOP Domain Sequences for d2cfia2:

Sequence; same for both SEQRES and ATOM records:

>d2cfia2 c.65.1.1 (A:1-203) 10-formyltetrahydrofolate dehydrogenase domain 1 {Human (Homo sapiens) [TaxId: 9606]}
mkiavigqslfgqevychlrkeghevvgvftvpdkdgkadplgleaekdgvpvfkysrwr
akgqalpdvvakyqalgaelnvlpfcsqfipmeiisaprhgsiiyhpsllprhrgasain
wtlihgdkkggfsifwaddgldtgdlllqkecevlpddtvstlynrflfpegikgmvqav
rliaegkaprlpqpeegatyegi

Timeline for d2cfia2:

• d2cfia2 first appeared in SCOP 1.73
  
• d2cfia2 appears in SCOPe 2.01
  
• d2cfia2 appears in the current release, SCOPe 2.08