SCOPe 2.08: Domain d2c07a1: 2c07 A:54-304

Lineage for d2c07a1 (2c07 A:54-304)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
   has additional subdomain(s) that are not in the common domain
   

6. Protein beta-keto acyl carrier protein reductase [51788] (8 species)

7. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [141877] (1 PDB entry)
   Uniprot Q86RB1 54-304

8. Domain d2c07a1: 2c07 A:54-304 [129577]
   complexed with so4

Details for d2c07a1

PDB Entry: 2c07, 1.5 Å

PDB Description: oxoacyl-acp reductase of plasmodium falciparum

PDB Compounds: (A:) 3-oxoacyl-(acyl-carrier protein) reductase

SCOPe Domain Sequences for d2c07a1:

Sequence, based on SEQRES records:

>d2c07a1 c.2.1.2 (A:54-304) beta-keto acyl carrier protein reductase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
kenyyycgenkvalvtgagrgigreiakmlaksvshvicisrtqkscdsvvdeiksfgye
ssgyagdvskkeeisevinkiltehknvdilvnnagitrdnlflrmkndewedvlrtnln
slfyitqpiskrminnrygriinissivgltgnvgqanyssskagvigftkslakelasr
nitvnaiapgfissdmtdkiseqikkniisnipagrmgtpeevanlacflssdksgying
rvfvidgglsp

Sequence, based on observed residues (ATOM records):

>d2c07a1 c.2.1.2 (A:54-304) beta-keto acyl carrier protein reductase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
kenyyycgenkvalvtgagrgigreiakmlaksvshvicisrtqkscdsvvdeiksfgye
ssgyagdvskkeeisevinkiltehknvdilvnnagitrdnlflrmkndewedvlrtnln
slfyitqpiskrminnrygriinissivgltgnvgqanyssskagvigftkslakelasr
nitvnaiapgfissiseqikkniisnipagrmgtpeevanlacflssdksgyingrvfvi
dgglsp

Timeline for d2c07a1:

• d2c07a1 first appeared in SCOP 1.73
  
• d2c07a1 appears in SCOPe 2.07