SCOPe 2.03: Domain d2b5ti_: 2b5t I:

Lineage for d2b5ti_ (2b5t I:)

1. Root: SCOPe 2.03

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.1: Serpins [56573] (1 superfamily)
   contains a cluster of helices and a beta-sandwich

4. Superfamily e.1.1: Serpins [56574] (2 families)

5. Family e.1.1.1: Serpins [56575] (17 proteins)
   automatically mapped to Pfam PF00079

6. Protein Antithrombin [56584] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56586] (27 PDB entries)
   Uniprot P01008

8. Domain d2b5ti_: 2b5t I: [127905]
   automated match to d2anti_
   complexed with gol, nag, so4

Details for d2b5ti_

PDB Entry: 2b5t, 2.1 Å

PDB Description: 2.1 angstrom structure of a nonproductive complex between antithrombin, synthetic heparin mimetic sr123781 and two s195a thrombin molecules

PDB Compounds: (I:) antithrombin-III

SCOPe Domain Sequences for d2b5ti_:

Sequence, based on SEQRES records:

>d2b5ti_ e.1.1.1 (I:) Antithrombin {Human (Homo sapiens) [TaxId: 9606]}
dictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfattfyqh
ladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffak
lncrlyrkankasklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraa
inkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfykadge
scsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlq
ewldeleemmlcvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvs
dafhkaflevneegseaaastavviagrslnpnrvcfkanrpflvfirevplntiifmgr
vanpcv

Sequence, based on observed residues (ATOM records):

>d2b5ti_ e.1.1.1 (I:) Antithrombin {Human (Homo sapiens) [TaxId: 9606]}
dictakprdipmnpmciyrspekipeatnrrvwelskansrfattfyqhladskndndni
flsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrkank
asklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnkteg
ritdvipseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyqeg
kfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleemml
cvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkaflevn
eegseaaastavviagrslnpnrvcfkanrpflvfirevplntiifmgrvanpcv

Timeline for d2b5ti_:

• d2b5ti_ first appeared in SCOP 1.73, called d2b5ti1
  
• d2b5ti_ appears in SCOPe 2.02
  
• d2b5ti_ appears in SCOPe 2.04
  
• d2b5ti_ appears in the current release, SCOPe 2.08