SCOPe 2.07: Domain d2ar0a1: 2ar0 A:6-529

Lineage for d2ar0a1 (2ar0 A:6-529)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families)

5. Family c.66.1.45: N-6 DNA Methylase-like [142606] (3 proteins)
   Pfam PF02384; contains C-terminal extension to the canonical fold and extra N-terminal all-alpha domain similar to the insert domain of the DAM family (88788)

6. Protein M.EcoKI [142609] (1 species)
   contains extra C-terminal structured region

7. Species Escherichia coli [TaxId:562] [142610] (1 PDB entry)
   Uniprot P08957 4-527

8. Domain d2ar0a1: 2ar0 A:6-529 [127185]
   complexed with unx

Details for d2ar0a1

PDB Entry: 2ar0, 2.8 Å

PDB Description: crystal structure of type i restriction enzyme ecoki m protein (ec 2.1.1.72) (m.ecoki)

PDB Compounds: (A:) Type I restriction enzyme EcoKI M protein

SCOPe Domain Sequences for d2ar0a1:

Sequence, based on SEQRES records:

>d2ar0a1 c.66.1.45 (A:6-529) M.EcoKI {Escherichia coli [TaxId: 562]}
ndlvaklwklcdnlrdggvsyqnyvnelasllflkmcketgqeaeylpegyrwddlksri
gqeqlqfyrkmlvhlgeddkklvqavfhnvsttitepkqitalvsnmdsldwyngahgks
rddfgdmyegllqknanetksgagqyftprpliktiihllkpqprevvqdpaagtagfli
eadryvksqtndlddldgdtqdfqihrafiglelvpgtrrlalmncllhdiegnldhgga
irlgntlgsdgenlpkahivatnppfgsaagtnitrtfvhptsnkqlcfmqhiietlhpg
graavvvpdnvlfeggkgtdirrdlmdkchlhtilrlptgifyaqgvktnvlfftkgtva
npnqdknctddvwvydlrtnmpsfgkrtpftdehlqpfervygedphglsprtegewsfn
aeetevadseenkntdqhlatsrwrkfsrewirtaksdsldiswlkdkdsidadslpepd
vlaaeamgelvqalseldalmrelgasdeadlqrqlleeafggv

Sequence, based on observed residues (ATOM records):

>d2ar0a1 c.66.1.45 (A:6-529) M.EcoKI {Escherichia coli [TaxId: 562]}
ndlvaklwklcdnlrdggvsyqnyvnelasllflkmcketgqeaeylpegyrwddlksri
gqeqlqfyrkmlvhlgeddkklvqavfhnvsttitepkqitalvsnmdsldwqyftprpl
iktiihllkpqprevvqdpaagtagflieadryvksqtndlddldgdtqdfqihrafigl
elvpgtrrlalmncllhdiegnldhggairlgntlgsdgenlpkahivatnppfgsaagt
nitrtfvhptsnkqlcfmqhiietlhpggraavvvpdnvlfeggkgtdirrdlmdkchlh
tilrlptgifyaqgvktnvlfftkgtvanpnqdknctddvwvydlrtnmpsfgkrtpftd
ehlqpfervygedphglsprtegewsfnaeetevadseenkntdqhlatsrwrkfsrewi
rtaksdsldiswlkdkdpepdvlaaeamgelvqalseldalmrelgasdeadlqrqllee
afggv

Timeline for d2ar0a1:

• d2ar0a1 first appeared in SCOP 1.73
  
• d2ar0a1 appears in SCOPe 2.06
  
• d2ar0a1 appears in the current release, SCOPe 2.08