Lineage for d2aotb_ (2aot B:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2129295Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
  4. 2129296Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families) (S)
  5. 2129827Family c.66.1.19: Histamine methyltransferase [75261] (1 protein)
  6. 2129828Protein Histamine methyltransferase [75262] (1 species)
  7. 2129829Species Human (Homo sapiens) [TaxId:9606] [75263] (7 PDB entries)
  8. 2129833Domain d2aotb_: 2aot B: [127099]
    automated match to d1jqda_
    complexed with 2pm, sah

Details for d2aotb_

PDB Entry: 2aot (more details), 1.9 Å

PDB Description: Histamine Methyltransferase Complexed with the Antihistamine Drug Diphenhydramine
PDB Compounds: (B:) Histamine N-methyltransferase

SCOPe Domain Sequences for d2aotb_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2aotb_ c.66.1.19 (B:) Histamine methyltransferase {Human (Homo sapiens) [TaxId: 9606]}
mrslfsdhgkyvesfrrflnhstehqcmqefmdkklpgiigrigdtkseikilsigggag
eidlqilskvqaqypgvcinnevvepsaeqiakykelvaktsnlenvkfawhketsseyq
srmlekkelqkwdfihmiqmlyyvkdipatlkffhsllgtnakmliivvsgssgwdklwk
kygsrfpqddlcqyitsddltqmldnlglkyecydllstmdisdcfidgnengdllwdfl
tetcnfnatappdlraelgkdlqepefsakkegkvlfnntlsfiviea

SCOPe Domain Coordinates for d2aotb_:

Click to download the PDB-style file with coordinates for d2aotb_.
(The format of our PDB-style files is described here.)

Timeline for d2aotb_: