SCOPe 2.04: Domain d1zjka1: 1zjk A:445-686

Lineage for d1zjka1 (1zjk A:445-686)

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)

6. Protein Mannan-binding lectin serine protease 2 (MASP-2), catalytic domain [110241] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [110242] (2 PDB entries)
   Uniprot O00187 366-686

8. Domain d1zjka1: 1zjk A:445-686 [125149]
   Other proteins in same PDB: d1zjka2, d1zjka3
   automatically matched to d1q3xa1

Details for d1zjka1

PDB Entry: 1zjk, 2.18 Å

PDB Description: crystal structure of the zymogen catalytic region of human masp-2

PDB Compounds: (A:) Mannan-binding lectin serine protease 2

SCOPe Domain Sequences for d1zjka1:

Sequence, based on SEQRES records:

>d1zjka1 b.47.1.2 (A:445-686) Mannan-binding lectin serine protease 2 (MASP-2), catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
iyggqkakpgdfpwqvlilggttaagallydnwvltaahavyeqkhdasaldirmgtlkr
lsphytqawseavfihegythdagfdndialiklnnkvvinsnitpiclprkeaesfmrt
ddigtasgwgltqrgflarnlmyvdipivdhqkctaayekppyprgsvtanmlcaglesg
gkdscrgdsggalvfldseterwfvggivswgsmncgeagqygvytkvinyipwieniis
df

Sequence, based on observed residues (ATOM records):

>d1zjka1 b.47.1.2 (A:445-686) Mannan-binding lectin serine protease 2 (MASP-2), catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
iyggqkakpgdfpwqvlilggttaagallydnwvltaahavyeqkhdasaldirmgtlkr
lsphytqawseavfihegythdagfdndialiklnnkvvinsnitpiclprkeaesfmrt
ddigtasgwgltqrgflarnlmyvdipivdhqkctaayekppyprgsvtanmlcaglesg
gkdscrgdsggalvfldseterwfvggivswgsmnceagqygvytkvinyipwieniisd
f

Timeline for d1zjka1:

• d1zjka1 first appeared in SCOP 1.73
  
• d1zjka1 appears in SCOPe 2.03
  
• d1zjka1 appears in SCOPe 2.05
  
• d1zjka1 appears in the current release, SCOPe 2.08