SCOPe 2.01: Domain d1z3na_: 1z3n A:

Lineage for d1z3na_ (1z3n A:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families)

5. Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
   Common fold covers whole protein structure

6. Protein automated matches [190169] (3 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188399] (33 PDB entries)

8. Domain d1z3na_: 1z3n A: [124411]
   automated match to d1el3a_
   complexed with 3na, ndp

Details for d1z3na_

PDB Entry: 1z3n, 1.04 Å

PDB Description: Human aldose reductase in complex with NADP+ and the inhibitor lidorestat at 1.04 angstrom

PDB Compounds: (A:) aldose reductase

SCOPe Domain Sequences for d1z3na_:

Sequence; same for both SEQRES and ATOM records:

>d1z3na_ c.1.7.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
masrillnngakmpilglgtwksppgqvteavkvaidvgyrhidcahvyqnenevgvaiq
eklreqvvkreelfivsklwctyhekglvkgacqktlsdlkldyldlylihwptgfkpgk
effpldesgnvvpsdtnildtwaameelvdeglvkaigisnfnhlqvemilnkpglkykp
avnqiechpyltqekliqycqskgivvtaysplgspdrpwakpedpslledprikaiaak
hnkttaqvlirfpmqrnlvvipksvtperiaenfkvfdfelssqdmttllsynrnwrvca
llsctshkdypfheef

Timeline for d1z3na_:

• d1z3na_ first appeared in SCOP 1.73, called d1z3na1
  
• d1z3na_ was called d1z3na1 in SCOP 1.75
  
• d1z3na_ appears in SCOPe 2.02
  
• d1z3na_ appears in the current release, SCOPe 2.08