SCOPe 2.02: Domain d1u5ia1: 1u5i A:515-700

Lineage for d1u5ia1 (1u5i A:515-700)

1. Root: SCOPe 2.02

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.39: EF Hand-like [47472] (4 superfamilies)
   core: 4 helices; array of 2 hairpins, opened

4. Superfamily a.39.1: EF-hand [47473] (12 families)
   Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop

5. Family a.39.1.8: Penta-EF-hand proteins [63550] (6 proteins)

6. Protein Calpain large subunit, C-terminal domain (domain IV) [47556] (3 species)

7. Species Rat (Rattus norvegicus), M-type [TaxId:10116] [47558] (2 PDB entries)

8. Domain d1u5ia1: 1u5i A:515-700 [119547]
   Other proteins in same PDB: d1u5ia2, d1u5ia3, d1u5ib1
   automatically matched to d1df0a1
   mutant

Details for d1u5ia1

PDB Entry: 1u5i, 2.86 Å

PDB Description: crystal structure analysis of rat m-calpain mutant lys10 thr

PDB Compounds: (A:) Calpain 2, large [catalytic] subunit precursor

SCOPe Domain Sequences for d1u5ia1:

Sequence, based on SEQRES records:

>d1u5ia1 a.39.1.8 (A:515-700) Calpain large subunit, C-terminal domain (domain IV) {Rat (Rattus norvegicus), M-type [TaxId: 10116]}
eieanieeieaneedigdgfrrlfaqlagedaeisafelqtilrrvlakrediksdgfsi
etckimvdmldedgsgklglkefyilwtkiqkyqkiyreidvdrsgtmnsyemrkaleea
gfklpcqlhqvivarfaddeliidfdnfvrclvrleilfkifkqldpentgtiqldlisw
lsfsvl

Sequence, based on observed residues (ATOM records):

>d1u5ia1 a.39.1.8 (A:515-700) Calpain large subunit, C-terminal domain (domain IV) {Rat (Rattus norvegicus), M-type [TaxId: 10116]}
eieanieeianeedigdgfrrlfaqlagedaeisafelqtilrrvlakksdgfsietcki
mvdmldedgsgklglkefyilwtkiqkyqkiyreidvdrsgtmnsyemrkaleeagfklp
cqlhqvivarfaddeliidfdnfvrclvrleilfkifkqldpentgtiqldliswlsfsv
l

Timeline for d1u5ia1:

• d1u5ia1 first appeared in SCOP 1.73
  
• d1u5ia1 appears in SCOPe 2.01
  
• d1u5ia1 appears in SCOPe 2.03
  
• d1u5ia1 appears in the current release, SCOPe 2.08