Lineage for Species: Human (Homo sapiens) [TaxId: 9606]
- Root: SCOPe 2.05
Class d: Alpha and beta proteins (a+b) [53931] (381 folds) 
Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
consists of two alpha+beta domains, C-terminal domain is mostly alpha helicalSuperfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) 
shares functional and structural similarities with the ATP-grasp fold and PIPK
Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
members organized in the groups and subfamiles specified by the comments
Protein Dual specificity mitogen-activated protein kinase kinase 1, Mek1 [118137] (1 species)
OPK group (?); MAPKK subfamily; serine/threonine kinaseSpecies Human (Homo sapiens) [TaxId:9606] [118138] (21 PDB entries)
Uniprot Q02750 61-381
PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:
- Domain(s) for 1s9j:
Domain d1s9ja_: 1s9j A: [112049]
complexed with atp, bbm, mg
- Domain(s) for 2p55:
Domain d2p55a_: 2p55 A: [149235]
automated match to d1s9ja_
complexed with atp, mg, mra
- Domain(s) for 3dv3:
Domain d3dv3a_: 3dv3 A: [174266]
automated match to d1s9ja_
complexed with atp, gol, mek, mg
- Domain(s) for 3dy7:
Domain d3dy7a_: 3dy7 A: [174388]
automated match to d1s9ja_
complexed with 1cx, atp, mg
- Domain(s) for 3e8n:
Domain d3e8na_: 3e8n A: [174753]
automated match to d1s9ja_
complexed with atp, mg, vra
- Domain(s) for 3eqb:
Domain d3eqba_: 3eqb A: [175155]
automated match to d1s9ja_
protein/RNA complex; complexed with atp, lug, mg
- Domain(s) for 3eqc:
Domain d3eqca_: 3eqc A: [209608]
automated match to d1s9ia_
complexed with 3bm, ags, ca, mg, na
- Domain(s) for 3eqd:
Domain d3eqda_: 3eqd A: [209609]
automated match to d1s9ia_
complexed with ags, ca, mg, na
- Domain(s) for 3eqf:
Domain d3eqfa_: 3eqf A: [209610]
automated match to d1s9ia_
complexed with ca, ksa, mg, na
- Domain(s) for 3eqg:
Domain d3eqga_: 3eqg A: [209611]
automated match to d1s9ia_
complexed with 4bm, adp, ca, mg, na
- Domain(s) for 3eqh:
Domain d3eqha_: 3eqh A: [209612]
automated match to d1s9ia_
complexed with 5bm, adp, ca, mg, na
- Domain(s) for 3eqi:
Domain d3eqia_: 3eqi A: [209613]
automated match to d1s9ia_
complexed with adp, ca, mg, na
- Domain(s) for 3v01:
Domain d3v01a_: 3v01 A: [217582]
automated match to d1s9ja_
complexed with 3v0, atp, mg
- Domain(s) for 3v04:
Domain d3v04a_: 3v04 A: [217583]
automated match to d1s9ja_
complexed with atp, mg, v04
- Domain(s) for 3vvh:
Domain d3vvha_: 3vvh A: [218119]
automated match to d1s9ja_
complexed with 4bm, atp, mg
Domain d3vvhb_: 3vvh B: [218120]
automated match to d1s9ja_
complexed with 4bm, atp, mg
Domain d3vvhc_: 3vvh C: [218121]
automated match to d1s9ja_
complexed with 4bm, atp, mg
- Domain(s) for 4lmn:
Domain d4lmna_: 4lmn A: [224705]
automated match to d1s9ja_
complexed with anp, eui, mg
- Domain(s) for 4mne:
Domain d4mnea_: 4mne A: [257091]
Other proteins in same PDB: d4mneb_, d4mnec_, d4mnef_, d4mneg_
automated match to d1s9ja_
complexed with 573, acp, cl, mg
Domain d4mned_: 4mne D: [257092]
Other proteins in same PDB: d4mneb_, d4mnec_, d4mnef_, d4mneg_
automated match to d1s9ja_
complexed with 573, acp, cl, mg
Domain d4mnee_: 4mne E: [257093]
Other proteins in same PDB: d4mneb_, d4mnec_, d4mnef_, d4mneg_
automated match to d1s9ja_
complexed with 573, acp, cl, mg
Domain d4mneh_: 4mne H: [257094]
Other proteins in same PDB: d4mneb_, d4mnec_, d4mnef_, d4mneg_
automated match to d1s9ja_
complexed with 573, acp, cl, mg
- Domain(s) for 4u7z:
Domain d4u7za_: 4u7z A: [260080]
automated match to d1s9ia_
complexed with 3ew, anp, mg
- Domain(s) for 4u80:
Domain d4u80a_: 4u80 A: [260254]
automated match to d1s9ia_
complexed with 3ex, anp, mg
- Domain(s) for 4u81:
Domain d4u81a_: 4u81 A: [260081]
automated match to d1s9ia_
complexed with 3ey, anp, mg
- Domain(s) for 5bx0:
Domain d5bx0a_: 5bx0 A: [280009]
automated match to d3eqca_
complexed with 4w5
More info for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Dual specificity mitogen-activated protein kinase kinase 1, Mek1
Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Dual specificity mitogen-activated protein kinase kinase 1, Mek1:
- Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Dual specificity mitogen-activated protein kinase kinase 1, Mek1 first appeared in SCOP 1.71
- Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Dual specificity mitogen-activated protein kinase kinase 1, Mek1 appears in SCOPe 2.04
- Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Dual specificity mitogen-activated protein kinase kinase 1, Mek1 appears in SCOPe 2.06
- Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Dual specificity mitogen-activated protein kinase kinase 1, Mek1 appears in the current release, SCOPe 2.08