SCOPe 2.05: Domain d1xdka_: 1xdk A:

Lineage for d1xdka_ (1xdk A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Retinoid-X receptor alpha (RXR-alpha) [48510] (2 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [48512] (3 PDB entries)
   Uniprot P28700 232-463

8. Domain d1xdka_: 1xdk A: [115164]
   Other proteins in same PDB: d1xdkb_, d1xdkf_
   complexed with co-activator peptide
   complexed with rea

Details for d1xdka_

PDB Entry: 1xdk, 2.9 Å

PDB Description: crystal structure of the rarbeta/rxralpha ligand binding domain heterodimer in complex with 9-cis retinoic acid and a fragment of the trap220 coactivator

PDB Compounds: (A:) Retinoic acid receptor RXR-alpha

SCOPe Domain Sequences for d1xdka_:

Sequence, based on SEQRES records:

>d1xdka_ a.123.1.1 (A:) Retinoid-X receptor alpha (RXR-alpha) {Mouse (Mus musculus) [TaxId: 10090]}
anedmpvekileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvewakr
iphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgai
fdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayck
hkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleap

Sequence, based on observed residues (ATOM records):

>d1xdka_ a.123.1.1 (A:) Retinoid-X receptor alpha (RXR-alpha) {Mouse (Mus musculus) [TaxId: 10090]}
anedmpvekileaelaveppndpvtnicqaadkqlftlvewakriphfselplddqvill
ragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmq
mdktelgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllr
lpalrsiglkclehlfffkligdtpidtflmemleap

Timeline for d1xdka_:

• d1xdka_ first appeared in SCOP 1.71
  
• d1xdka_ appears in SCOPe 2.04
  
• d1xdka_ appears in SCOPe 2.06
  
• d1xdka_ appears in the current release, SCOPe 2.08