Lineage for Protein: Phenylacetone monooxygenase

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2849308Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
    core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander
  4. 2849309Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (9 families) (S)
  5. 2849878Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (25 proteins)
    duplication: both domains have similar folds and functions
    most members of the family contain common C-terminal alpha+beta domain
  6. 2850147Protein Phenylacetone monooxygenase [110440] (1 species)

Species:

  • 2850148Thermobifida fusca [TaxId:2021] [110441] (6 PDB entries)
    Uniprot Q5YS95 # 55% sequence identity; Nocardia farcinica TaxID:37329
    1. Domains for 1w4x:
      1. 2850149Domain d1w4xa1: 1w4x A:10-154,A:390-542 [109171]
        complexed with fad, so4
        has additional insertions and/or extensions that are not grouped together
      2. 2850150Domain d1w4xa2: 1w4x A:155-389 [109172]
        complexed with fad, so4
        has additional insertions and/or extensions that are not grouped together
        heterogeneous fold; applies to domains that adopt a different fold than the exemplar domain but has similar sequence and number of secondary structures
    2. Domains for 2ylr:
      1. 2850157Domain d2ylra1: 2ylr A:10-154,A:390-542 [207663]
        automated match to d1w4xa1
        complexed with fad, nap
        has additional insertions and/or extensions that are not grouped together
      2. 2850158Domain d2ylra2: 2ylr A:155-389 [207664]
        automated match to d1w4xa2
        complexed with fad, nap
        has additional insertions and/or extensions that are not grouped together
        heterogeneous fold; applies to domains that adopt a different fold than the exemplar domain but has similar sequence and number of secondary structures
    3. Domains for 2yls:
      1. 2850155Domain d2ylsa1: 2yls A:11-154,A:390-542 [207665]
        automated match to d1w4xa1
        complexed with fad, nap
        has additional insertions and/or extensions that are not grouped together
      2. 2850156Domain d2ylsa2: 2yls A:155-389 [207666]
        automated match to d1w4xa2
        complexed with fad, nap
        has additional insertions and/or extensions that are not grouped together
        heterogeneous fold; applies to domains that adopt a different fold than the exemplar domain but has similar sequence and number of secondary structures
    4. Domains for 2ylt:
      1. 2850159Domain d2ylta1: 2ylt A:12-154,A:390-542 [207667]
        automated match to d1w4xa1
        complexed with fad, mes, nap
        has additional insertions and/or extensions that are not grouped together
      2. 2850160Domain d2ylta2: 2ylt A:155-389 [207668]
        automated match to d1w4xa2
        complexed with fad, mes, nap
        has additional insertions and/or extensions that are not grouped together
        heterogeneous fold; applies to domains that adopt a different fold than the exemplar domain but has similar sequence and number of secondary structures
    5. Domains for 4c74:
      1. 2850153Domain d4c74a1: 4c74 A:12-154,A:390-542 [236517]
        automated match to d1w4xa1
        complexed with fad, n01, p6g
        has additional insertions and/or extensions that are not grouped together
      2. 2850154Domain d4c74a2: 4c74 A:155-389 [236518]
        automated match to d1w4xa2
        complexed with fad, n01, p6g
        has additional insertions and/or extensions that are not grouped together
        heterogeneous fold; applies to domains that adopt a different fold than the exemplar domain but has similar sequence and number of secondary structures
    6. Domains for 4ovi:
      1. 2850151Domain d4ovia1: 4ovi A:12-154,A:390-542 [257336]
        automated match to d1w4xa1
        complexed with act, cl, fad, gol, n01, pge
        has additional insertions and/or extensions that are not grouped together
      2. 2850152Domain d4ovia2: 4ovi A:155-389 [257337]
        automated match to d1w4xa2
        complexed with act, cl, fad, gol, n01, pge
        has additional insertions and/or extensions that are not grouped together
        heterogeneous fold; applies to domains that adopt a different fold than the exemplar domain but has similar sequence and number of secondary structures

More info for Protein Phenylacetone monooxygenase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains

Timeline for Protein Phenylacetone monooxygenase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains:

  • Protein Phenylacetone monooxygenase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains first appeared in SCOP 1.69
  • Protein Phenylacetone monooxygenase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains appears in SCOPe 2.07