SCOPe 2.02: Domain d1tqna_: 1tqn A:

Lineage for d1tqna_ (1tqn A:)

1. Root: SCOPe 2.02

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.1: Cytochrome P450 [48265] (23 proteins)

6. Protein Mammalian cytochrome P450 3a4 [109958] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [109959] (6 PDB entries)
   Uniprot P08684

8. Domain d1tqna_: 1tqn A: [107238]
   complexed with hem

Details for d1tqna_

PDB Entry: 1tqn, 2.05 Å

PDB Description: Crystal Structure of Human Microsomal P450 3A4

PDB Compounds: (A:) cytochrome p450 3a4

SCOPe Domain Sequences for d1tqna_:

Sequence, based on SEQRES records:

>d1tqna_ a.104.1.1 (A:) Mammalian cytochrome P450 3a4 {Human (Homo sapiens) [TaxId: 9606]}
hshglfkklgipgptplpflgnilsyhkgfcmfdmechkkygkvwgfydgqqpvlaitdp
dmiktvlvkecysvftnrrpfgpvgfmksaisiaedeewkrlrsllsptftsgklkemvp
iiaqygdvlvrnlrreaetgkpvtlkdvfgaysmdvitstsfgvnidslnnpqdpfvent
kkllrfdfldpfflsitvfpflipilevlnicvfprevtnflrksvkrmkesrledtqkh
rvdflqlmidsqnsketeshkalsdlelvaqsiififagyettssvlsfimyelathpdv
qqklqeeidavlpnkapptydtvlqmeyldmvvnetlrlfpiamrlervckkdveingmf
ipkgvvvmipsyalhrdpkywtepekflperfskknkdnidpyiytpfgsgprncigmrf
almnmklalirvlqnfsfkpcketqiplklslggllqpekpvvlkvesrdgt

Sequence, based on observed residues (ATOM records):

>d1tqna_ a.104.1.1 (A:) Mammalian cytochrome P450 3a4 {Human (Homo sapiens) [TaxId: 9606]}
hshglfkklgipgptplpflgnilsyhkgfcmfdmechkkygkvwgfydgqqpvlaitdp
dmiktvlvkecysvftnrrpfgpvgfmksaisiaedeewkrlrsllsptftsgklkemvp
iiaqygdvlvrnlrreaetgkpvtlkdvfgaysmdvitstsfgvnidslnnpqdpfvent
kkllrfdfldpfflsitvfpflipilevlnicvfprevtnflrksvkrmkesrledtqkh
rvdflqlmidsqnsshkalsdlelvaqsiififagyettssvlsfimyelathpdvqqkl
qeeidavlpnkapptydtvlqmeyldmvvnetlrlfpiamrlervckkdveingmfipkg
vvvmipsyalhrdpkywtepekflperfskknkdnidpyiytpfgsgprncigmrfalmn
mklalirvlqnfsfkpcketqiplklslggllqpekpvvlkvesrdgt

Timeline for d1tqna_:

• d1tqna_ first appeared in SCOP 1.69
  
• d1tqna_ appears in SCOPe 2.01
  
• d1tqna_ appears in SCOPe 2.03
  
• d1tqna_ appears in the current release, SCOPe 2.08