SCOPe 2.01: Domain d1oiub1: 1oiu B:177-309

Lineage for d1oiub1 (1oiu B:177-309)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.74: Cyclin-like [47953] (1 superfamily)
   core: 5 helices; one helix is surrounded by the others

4. Superfamily a.74.1: Cyclin-like [47954] (3 families)
   duplication: consists of two domains of this fold

5. Family a.74.1.1: Cyclin [47955] (8 proteins)

6. Protein Cyclin A [47956] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [47957] (35 PDB entries)
   Uniprot P20248 175-432

8. Domain d1oiub1: 1oiu B:177-309 [103959]
   Other proteins in same PDB: d1oiua_, d1oiuc_
   complexed with mg, n76, sgm

Details for d1oiub1

PDB Entry: 1oiu, 2 Å

PDB Description: structure of human thr160-phospho cdk2/cyclin a complexed with a 6-cyclohexylmethyloxy-2-anilino-purine inhibitor

PDB Compounds: (B:) cyclin a2

SCOPe Domain Sequences for d1oiub1:

Sequence; same for both SEQRES and ATOM records:

>d1oiub1 a.74.1.1 (B:177-309) Cyclin A {Human (Homo sapiens) [TaxId: 9606]}
dyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetlhlav
nyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkqvlrmeh
lvlkvltfdlaap

Timeline for d1oiub1:

• d1oiub1 first appeared in SCOP 1.69
  
• d1oiub1 appears in SCOP 1.75
  
• d1oiub1 appears in SCOPe 2.02
  
• d1oiub1 appears in the current release, SCOPe 2.08