SCOPe 2.08: Family d.110.3.7: Hypoxia-inducible factor Hif2a, C-terminal domain

Lineage for Family d.110.3.7: Hypoxia-inducible factor Hif2a, C-terminal domain

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.110: Profilin-like [55769] (10 superfamilies)
   core: 2 alpha-helices and 5-stranded antiparallel sheet: order 21543; 3 layers: alpha/beta/alpha

4. Superfamily d.110.3: PYP-like sensor domain (PAS domain) [55785] (8 families)
   alpha-beta(2)-alpha(2)-beta(3)

5. Family d.110.3.7: Hypoxia-inducible factor Hif2a, C-terminal domain [103184] (2 proteins)
   contains PAC motif

Proteins:

1. Hypoxia-inducible factor Hif2a, C-terminal domain [103185] (1 species)
   endothelial pas domain protein 1, EPAS-1

   • Species Human (Homo sapiens) [TaxId:9606] [103186] (1 PDB entry)

2. automated matches [191006] (1 species)
   not a true protein

   • Species Human (Homo sapiens) [TaxId:9606] [188753] (22 PDB entries)

More info for Family d.110.3.7: Hypoxia-inducible factor Hif2a, C-terminal domain

Timeline for Family d.110.3.7: Hypoxia-inducible factor Hif2a, C-terminal domain:

• Family d.110.3.7: Hypoxia-inducible factor Hif2a, C-terminal domain first appeared in SCOP 1.67
  
• Family d.110.3.7: Hypoxia-inducible factor Hif2a, C-terminal domain appears in SCOPe 2.07