Lineage for d1s9ia_ (1s9i A:)
- Root: SCOPe 2.08
Class d: Alpha and beta proteins (a+b) [53931] (396 folds) 
Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
consists of two alpha+beta domains, C-terminal domain is mostly alpha helicalSuperfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) 
shares functional and structural similarities with the ATP-grasp fold and PIPKFamily d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
members organized in the groups and subfamiles specified by the comments
Protein Dual specificity mitogen-activated protein kinase kinase 2, Mek2 [118135] (1 species)
OPK group (?); MAPKK subfamily; serine/threonine kinaseSpecies Human (Homo sapiens) [TaxId:9606] [118136] (1 PDB entry)
Uniprot P36507 60-393
Domain d1s9ia_: 1s9i A: [112047]
complexed with 5ea, atp, mg
Details for d1s9ia_
PDB Entry: 1s9i (more details), 3.2 Å
PDB Description: X-ray structure of the human mitogen-activated protein kinase kinase 2 (MEK2)in a complex with ligand and MgATP
PDB Compounds: (A:) Dual specificity mitogen-activated protein kinase kinase 2SCOPe Domain Sequences for d1s9ia_:
Sequence, based on SEQRES records: (download)
>d1s9ia_ d.144.1.7 (A:) Dual specificity mitogen-activated protein kinase kinase 2, Mek2 {Human (Homo sapiens) [TaxId: 9606]}
qkakvgelkdddferiselgagnggvvtkvqhrpsglimarklihleikpairnqiirel
qvlhecnspyivgfygafysdgeisicmehmdggsldqvlkeakripeeilgkvsiavlr
glaylrekhqimhrdvkpsnilvnsrgeiklcdfgvsgqlidsmansfvgtrsymaperl
qgthysvqsdiwsmglslvelavgrypipppdakeleaifgrpvvdgeegephsisprpr
ppgrpvsghgmdsrpamaifelldyivnepppklpngvftpdfqefvnkcliknpaerad
lkmltnhtfikrseveevdfagwlcktlrlnqpg
Sequence, based on observed residues (ATOM records): (download)
>d1s9ia_ d.144.1.7 (A:) Dual specificity mitogen-activated protein kinase kinase 2, Mek2 {Human (Homo sapiens) [TaxId: 9606]}
qkakvgelkdddferiselgagnggvvtkvqhrpsglimarklihleikpairnqiirel
qvlhecnspyivgfygafysdgeisicmehmdggsldqvlkeakripeeilgkvsiavlr
glaylrekhqimhrdvkpsnilvnsrgeiklcdfgvsgqlidsmvgtrsymaperlqgth
ysvqsdiwsmglslvelavgrypipppdakeleaifgrpvvdrpamaifelldyivnepp
pklpngvftpdfqefvnkcliknpaeradlkmltnhtfikrseveevdfagwlcktlrln
qpg
SCOPe Domain Coordinates for d1s9ia_:
Click to download the PDB-style file with coordinates for d1s9ia_.
(The format of our PDB-style files is described here.)
(The format of our PDB-style files is described here.)
Timeline for d1s9ia_:
- d1s9ia_ first appeared in SCOP 1.71
- d1s9ia_ appears in SCOPe 2.07
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