SCOPe 2.07: Domain d1pkxa2: 1pkx A:201-592

Lineage for d1pkxa2 (1pkx A:201-592)

Root: SCOPe 2.07
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
Fold c.97: Cytidine deaminase-like [53926] (2 superfamilies)
core: alpha-beta(2)-(alpha-beta)2; 3 layers (a/b/a); mixed beta-sheet of 4 strands, order 2134; strand 1 is antiparallel to the rest
Superfamily c.97.1: Cytidine deaminase-like [53927] (7 families)
contains extra C-terminal strand 5, order 21345

Family c.97.1.4: AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC [64198] (2 proteins)
duplication: consists of two domains of this fold with extra secondary structures within and in between the two core motifs

Protein AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC [64199] (3 species)
Species Human (Homo sapiens) [TaxId:9606] [102716] (3 PDB entries)
Domain d1pkxa2: 1pkx A:201-592 [94839]
Other proteins in same PDB: d1pkxa1, d1pkxb1, d1pkxc1, d1pkxd1
complexed with k, xmp

Details for d1pkxa2

PDB Entry: 1pkx (more details), 1.9 Å

PDB Description: Crystal Structure of human ATIC in complex with XMP

PDB Compounds: (A:) Bifunctional purine biosynthesis protein PURH

SCOPe Domain Sequences for d1pkxa2:

Sequence, based on SEQRES records: (download)

>d1pkxa2 c.97.1.4 (A:201-592) AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC {Human (Homo sapiens) [TaxId: 9606]}
vsqmplrygmnphqtpaqlytlqpklpitvlngapgfinlcdalnawqlvkelkealgip
aaasfkhvspagaavgiplsedeakvcmvydlyktltpisaayarargadrmssfgdfva
lsdvcdvptakiisrevsdgiiapgyeeealtilskkkngnycvlqmdqsykpdenevrt
lfglhlsqkrnngvvdkslfsnvvtknkdlpesalrdlivatiavkytqsnsvcyakngq
vigigagqqsrihctrlagdkanywwlrhhpqvlsmkfktgvkraeisnaidqyvtgtig
ededlikwkalfeevpellteaekkewvekltevsissdaffpfrdnvdrakrsgvayia
apsgsaadkvvieacdelgiilahtnlrlfhh

Sequence, based on observed residues (ATOM records): (download)

>d1pkxa2 c.97.1.4 (A:201-592) AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC {Human (Homo sapiens) [TaxId: 9606]}
vsqmplrygmnphqtpaqlytlqpklpitvlngapgfinlcdalnawqlvkelkealgip
aaasfkhvspagaavgiplsedeakvcmvydlyktltpisaayarargadrmssfgdfva
lsdvcdvptakiisrevsdgiiapgyeeealtilskkkngnycvlqmdqsykpdenevrt
lfglhlsqkrnngvvdkslfsnvvtknkdlpesalrdlivatiavkytqsnsvcyakngq
vigigagqqsrihctrlagdkanywwlrhhpqvlsmkfktgvaeisnaidqyvtgtiged
edlikwkalfeevpellteaekkewvekltevsissdaffpfrdnvdrakrsgvayiaap
sgsaadkvvieacdelgiilahtnlrlfhh

SCOPe Domain Coordinates for d1pkxa2:

Click to download the PDB-style file with coordinates for d1pkxa2.
(The format of our PDB-style files is described here.)

Timeline for d1pkxa2: