Lineage for d1iria_ (1iri A:)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2515496Fold c.80: SIS domain [53696] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 5 strands, order 21345
  4. 2515497Superfamily c.80.1: SIS domain [53697] (4 families) (S)
  5. 2515555Family c.80.1.2: Phosphoglucose isomerase, PGI [53701] (2 proteins)
    permutation of the double-SIS domain fold
    automatically mapped to Pfam PF00342
  6. 2515556Protein Phosphoglucose isomerase, PGI [53702] (8 species)
    moonlights as neuroleukin, autocrine motility factor, and differentiation mediator
  7. 2515567Species Human (Homo sapiens) [TaxId:9606] [64176] (7 PDB entries)
  8. 2515577Domain d1iria_: 1iri A: [71343]
    complexed with e4p

Details for d1iria_

PDB Entry: 1iri (more details), 2.4 Å

PDB Description: Crystal structure of human autocrine motility factor complexed with an inhibitor
PDB Compounds: (A:) autocrine motility factor

SCOPe Domain Sequences for d1iria_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1iria_ c.80.1.2 (A:) Phosphoglucose isomerase, PGI {Human (Homo sapiens) [TaxId: 9606]}
maaltrdpqfqklqqwyrehrselnlrrlfdankdrfnhfsltlntnhghilvdysknlv
tedvmrmlvdlaksrgveaarermfngekinytegravlhvalrnrsntpilvdgkdvmp
evnkvldkmksfcqrvrsgdwkgytgktitdvinigiggsdlgplmvtealkpyssggpr
vwyvsnidgthiaktlaqlnpesslfiiasktfttqetitnaetakewflqaakdpsava
khfvalstnttkvkefgidpqnmfefwdwvggryslwsaiglsialhvgfdnfeqllsga
hwmdqhfrttpleknapvllallgiwyincfgcethamlpydqylhrfaayfqqgdmesn
gkyitksgtrvdhqtgpivwgepgtngqhafyqlihqgtkmipcdflipvqtqhpirkgl
hhkillanflaqtealmrgksteearkelqaagkspedlerllphkvfegnrptnsivft
kltpfmlgalvamyehkifvqgiiwdinsfdqwgvelgkqlakkiepeldgsaqvtshda
stnglinfikqqrearv

SCOPe Domain Coordinates for d1iria_:

Click to download the PDB-style file with coordinates for d1iria_.
(The format of our PDB-style files is described here.)

Timeline for d1iria_: