SCOPe 2.07: Family c.80.1.2: Phosphoglucose isomerase, PGI

Lineage for Family c.80.1.2: Phosphoglucose isomerase, PGI

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.80: SIS domain [53696] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 5 strands, order 21345

4. Superfamily c.80.1: SIS domain [53697] (4 families)

5. Family c.80.1.2: Phosphoglucose isomerase, PGI [53701] (2 proteins)
   permutation of the double-SIS domain fold
   automatically mapped to Pfam PF00342

Proteins:

1. Phosphoglucose isomerase, PGI [53702] (8 species)
   moonlights as neuroleukin, autocrine motility factor, and differentiation mediator

   1. Species Bacillus stearothermophilus [TaxId:1422] [53704] (4 PDB entries)

   2. Species Colias eurytheme [TaxId:42296] [311110] (1 PDB entry)

   3. Species Human (Homo sapiens) [TaxId:9606] [64176] (7 PDB entries)

   4. Species Mouse (Mus musculus) [TaxId:10090] [117732] (3 PDB entries)
      Uniprot P06745

   5. Species Pig (Sus scrofa) [TaxId:9823] [75316] (2 PDB entries)

   6. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [53703] (6 PDB entries)

   7. Species Trypanosoma brucei [TaxId:5702] [255518] (2 PDB entries)

   8. Species Trypanosome (Leishmania mexicana) [TaxId:5665] [110728] (2 PDB entries)
      Uniprot P42861

2. automated matches [190137] (6 species)
   not a true protein

   1. Species Elizabethkingia anophelis [TaxId:1338011] [349955] (2 PDB entries)

   2. Species Escherichia coli [TaxId:668369] [190004] (1 PDB entry)

   3. Species Mouse (Mus musculus) [TaxId:10090] [187571] (9 PDB entries)

   4. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [186861] (1 PDB entry)

   5. Species Staphylococcus aureus [TaxId:93062] [188767] (1 PDB entry)

   6. Species Vibrio cholerae [TaxId:666] [225688] (1 PDB entry)

More info for Family c.80.1.2: Phosphoglucose isomerase, PGI

Timeline for Family c.80.1.2: Phosphoglucose isomerase, PGI:

• Family c.80.1.2: Phosphoglucose isomerase, PGI first appeared (with stable ids) in SCOP 1.55
  
• Family c.80.1.2: Phosphoglucose isomerase, PGI appears in SCOPe 2.06
  
• Family c.80.1.2: Phosphoglucose isomerase, PGI appears in the current release, SCOPe 2.08