SCOP 1.75: Domain d1np3a2: 1np3 A:1-182

Lineage for d1np3a2 (1np3 A:1-182)

Root: SCOP 1.75
Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

Family c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain [51868] (18 proteins)
the beta-sheet is extended to 8 strands, order 32145678; strands 7 & 8 are antiparallel to the rest
C-terminal domains also show some similarity

Protein Class I ketol-acid reductoisomerase (KARI) [89532] (1 species)
Species Pseudomonas aeruginosa [TaxId:287] [89533] (1 PDB entry)
Domain d1np3a2: 1np3 A:1-182 [85947]
Other proteins in same PDB: d1np3a1, d1np3b1, d1np3c1, d1np3d1

Details for d1np3a2

PDB Entry: 1np3 (more details), 2 Å

PDB Description: Crystal structure of class I acetohydroxy acid isomeroreductase from Pseudomonas aeruginosa

PDB Compounds: (A:) Ketol-acid reductoisomerase

SCOP Domain Sequences for d1np3a2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1np3a2 c.2.1.6 (A:1-182) Class I ketol-acid reductoisomerase (KARI) {Pseudomonas aeruginosa [TaxId: 287]}
mrvfydkdcdlsiiqgkkvaiigygsqghahacnlkdsgvdvtvglrsgsatvakaeahg
lkvadvktavaaadvvmiltpdefqgrlykeeiepnlkkgatlafahgfsihynqvvpra
dldvimiapkapghtvrsefvkgggipdliaiyqdasgnaknvalsyacgvgggrtgiie
tt

SCOP Domain Coordinates for d1np3a2:

Click to download the PDB-style file with coordinates for d1np3a2.
(The format of our PDB-style files is described here.)

Timeline for d1np3a2: