PDB entry 7zy4

View 7zy4 on RCSB PDB site
Description: Crystal structure of human CstF77 in complex with hFip1
Class: gene regulation
Keywords: Complex, 3' end processing, CstF, CPSF, GENE REGULATION
Deposited on 2022-05-23, released 2022-09-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-09-14, with a file datestamp of 2022-09-09.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cleavage stimulation factor subunit 3
    Species: Homo sapiens [TaxId:9606]
    Gene: Cstf3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12996 (3-311)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d7zy4a_
  • Chain 'B':
    Compound: Cleavage stimulation factor subunit 3
    Species: Homo sapiens [TaxId:9606]
    Gene: Cstf3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12996 (3-311)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d7zy4b_
  • Chain 'C':
    Compound: hFip1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7ZY4 (0-37)
  • Chain 'D':
    Compound: hFip1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7ZY4 (0-37)
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >7zy4A (A:)
    snantpqeaqqvdmwkkyiqweksnplrtedqtlitkrvmfayeqcllvlghhpdiwyea
    aqyleqsskllaekgdmnnaklfsdeaaniyeraistllkknmllyfayadyeesrmkye
    kvhsiynrllaiedidptlvyiqymkfarraegiksgrmifkkaredtrtrhhvyvtaal
    meyycskdksvafkifelglkkygdipeyvlayidylshlnednntrvlfervltsgslp
    peksgeiwarflafesnigdlasilkvekrrftafkeeyegketallvdrykfmdlypcs
    aselkalgykdv
    

    Sequence, based on observed residues (ATOM records): (download)
    >7zy4A (A:)
    qeaqqvdmwkkyiqweksnplrtedqtlitkrvmfayeqcllvlghhpdiwyeaaqyleq
    sskllaekgdmnnaklfsdeaaniyeraistllkknmllyfayadyeesrmkyekvhsiy
    nrllaiedidptlvyiqymkfarraegiksgrmifkkaredtrtrhhvyvtaalmeyycs
    kdksvafkifelglkkygdipeyvlayidylshlnednntrvlfervltsgslppeksge
    iwarflafesnigdlasilkvekrrftafkeeyegketallvdrykfmdlypcsaselka
    lgykd
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >7zy4B (B:)
    snantpqeaqqvdmwkkyiqweksnplrtedqtlitkrvmfayeqcllvlghhpdiwyea
    aqyleqsskllaekgdmnnaklfsdeaaniyeraistllkknmllyfayadyeesrmkye
    kvhsiynrllaiedidptlvyiqymkfarraegiksgrmifkkaredtrtrhhvyvtaal
    meyycskdksvafkifelglkkygdipeyvlayidylshlnednntrvlfervltsgslp
    peksgeiwarflafesnigdlasilkvekrrftafkeeyegketallvdrykfmdlypcs
    aselkalgykdv
    

    Sequence, based on observed residues (ATOM records): (download)
    >7zy4B (B:)
    pqeaqqvdmwkkyiqweksnplrtedqtlitkrvmfayeqcllvlghhpdiwyeaaqyle
    qsskllaekgdmnnaklfsdeaaniyeraistllkknmllyfayadyeesrmkyekvhsi
    ynrllaiedidptlvyiqymkfarraegiksgrmifkkaredtrtrhhvyvtaalmeyyc
    skdksvafkifelglkkygdipeyvlayidylshlnednntrvlfervltsgslppeksg
    eiwarflafesnigdlasilkvekrrftafkeeyegketallvdrykfmdlypcsaselk
    algykd
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.