PDB entry 7amh

View 7amh on RCSB PDB site
Description: SmBRD3(2), Second Bromodomain of Bromodomain 3 from Schistosoma mansoni in complex with DM-A-33, an iBET726 analogue
Class: protein binding
Keywords: bromo domain, methyllysine binding, epigenetic reader domain, inhibitor, complex, PROTEIN BINDING
Deposited on 2020-10-08, released 2021-10-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-10-20, with a file datestamp of 2021-10-15.
Experiment type: XRAY
Resolution: 1.86 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Putative bromodomain-containing protein 3, brd3
    Species: Schistosoma mansoni [TaxId:6183]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7amha_
  • Chain 'B':
    Compound: Putative bromodomain-containing protein 3, brd3
    Species: Schistosoma mansoni [TaxId:6183]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7amhb_
  • Heterogens: RN5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7amhA (A:)
spkreyeernvgkrlrlsealkacsnilkdissqryrdlnhfflkpvdvvalglhdyydv
vkkamdlstiktklesgqyhtkydfaddvrlmfnncykyngedsevarvgkqlqaifden
fakvpddes

    Sequence, based on observed residues (ATOM records): (download) 
    >7amhA (A:)
lrlsealkacsnilkdissqryrdlnhfflkpvdvvalglhdyydvvkkamdlstiktkl
esgqyhtkydfaddvrlmfnncykyngedsevarvgkqlqaifdenfakvpdd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7amhB (B:)
spkreyeernvgkrlrlsealkacsnilkdissqryrdlnhfflkpvdvvalglhdyydv
vkkamdlstiktklesgqyhtkydfaddvrlmfnncykyngedsevarvgkqlqaifden
fakvpddes

    Sequence, based on observed residues (ATOM records): (download) 
    >7amhB (B:)
rlsealkacsnilkdissqryrdlnhfflkpvdvvalglhdyydvvkkamdlstiktkle
sgqyhtkydfaddvrlmfnncykyngedsevarvgkqlqaifdenfakvpdde