PDB entry 7aem

View 7aem on RCSB PDB site
Description: Studies Towards a Reversible EGFR C797S Triple Mutant Inhibitor Series
Class: cell cycle
Keywords: egfr, cell cycle
Deposited on 2020-09-17, released 2021-04-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-04-07, with a file datestamp of 2021-04-02.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Epidermal growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: EGFR, ERBB, ERBB1, HER1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7aema_
  • Heterogens: 6GY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7aemA (A:)
gstslykkagsenlyfqgsgeapnqallrilketefkkikvlgsgafgtvykglwipege
kvkipvaikelreatspkankeildeayvmasvdnphvcrllgicltstvqlitqlmpfg
clldyvrehkdnigsqyllnwcvqiakgmnyledrrlvhrdlaarnvlvktpqhvkitdf
glakllgaeekeyhaeggkvpikwmalesilhriythqsdvwsygvtvwelmtfgskpyd
gipaseissilekgerlpqppictidvymimvkcwmidadsrpkfreliiefskmardpq
rylviqgdermhlpsptdsnfyralmdeedmddvvdadeylipqqg

    Sequence, based on observed residues (ATOM records): (download) 
    >7aemA (A:)
sgeapnqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelatspkan
keildeayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsqylln
wcvqiakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhaeggkv
pikwmalesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpqp
pictidvymimvkcwmidadsrpkfreliiefskmardpqrylviqgdermhlplmdeed
mddvvdadeyli