PDB entry 6u7e

View 6u7e on RCSB PDB site
Description: HCoV-229E RBD Class III in complex with human APN
Class: hydrolase/viral protein
Keywords: CoV, coronavirus, 229E, spike glycoprotein, APN, S-protein, HYDROLASE-VIRAL PROTEIN complex
Deposited on 2019-09-02, released 2019-11-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-11-13, with a file datestamp of 2019-11-08.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aminopeptidase N
    Species: Homo sapiens [TaxId:9606]
    Gene: ANPEP, APN, CD13, PEPN
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6u7ea1, d6u7ea2, d6u7ea3, d6u7ea4
  • Chain 'B':
    Compound: Aminopeptidase N
    Species: Homo sapiens [TaxId:9606]
    Gene: ANPEP, APN, CD13, PEPN
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6u7eb1, d6u7eb2, d6u7eb3, d6u7eb4
  • Chain 'C':
    Compound: Spike glycoprotein
    Species: Human coronavirus 229E [TaxId:11137]
    Database cross-references and differences (RAF-indexed):
    • PDB 6U7E
  • Chain 'D':
    Compound: Spike glycoprotein
    Species: Human coronavirus 229E [TaxId:11137]
    Database cross-references and differences (RAF-indexed):
    • PDB 6U7E
  • Heterogens: ZN, NAG, BMA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6u7eA (A:)
ggrpdqskawnryrlpntlkpdsyrvtlrpyltpndrglyvfkgsstvrftckeatdvii
ihskklnytlsqghrvvlrgvggsqppdidktelvepteylvvhlkgslvkdsqyemdse
fegeladdlagfyrseymegnvrkvvattqmqaadarksfpcfdepamkaefnitlihpk
dltalsnmlpkgpstplpedpnwnvtefhttpkmstyllafivsefdyvekqasngvlir
iwarpsaiaaghgdyalnvtgpilnffaghydtpyplpksdqiglpdfnagamenwglvt
yrensllfdplsssssnkervvtviahelahqwfgnlvtiewwndlwlnegfasyveylg
adyaeptwnlkdlmvlndvyrvmavdalasshplstpaseintpaqiselfdaisyskga
svlrmlssflsedvfkqglasylhtfayqntiylnlwdhlqeavnnrsiqlpttvrdimn
rwtlqmgfpvitvdtstgtlsqehflldpdsnvtrpsefnyvwivpitsirdgrqqqdyw
lidvraqndlfstsgnewvllnlnvtgyyrvnydeenwrkiqtqlqrdhsaipvinraqi
indafnlasahkvpvtlalnntlflieerqympweaalsslsyfklmfdrsevygpmkny
lkkqvtplfihfrnntnnwreipenlmdqysevnaistacsngvpeceemvsglfkqwme
npnnnpihpnlrstvycnaiaqggeeewdfaweqfrnatlvneadklraalacskelwil
nrylsytlnpdlirkqdatstiisitnnvigqglvwdfvqsnwkklfndygggsfsfsnl
iqavtrrfsteyelqqleqfkkdneetgfgsgtraleqalektkanikwvkenkevvlqw
ftensk

    Sequence, based on observed residues (ATOM records): (download) 
    >6u7eA (A:)
skawnryrlpntlkpdsyrvtlrpyltpndrglyvfkgsstvrftckeatdviiihskkl
nytlsqghrvvlrgvggsqppdidktelvepteylvvhlkgslvkdsqyemdsefegela
ddlagfyrseymegnvrkvvattqmqaadarksfpcfdepamkaefnitlihpkdltals
nmlpkgpstplpedpnwnvtefhttpkmstyllafivsefdyvekqasngvliriwarps
aiaaghgdyalnvtgpilnffaghydtpyplpksdqiglpdfnagamenwglvtyrensl
lfdplsssssnkervvtviahelahqwfgnlvtiewwndlwlnegfasyveylgadyaep
twnlkdlmvlndvyrvmavdalasshplstpaseintpaqiselfdaisyskgasvlrml
ssflsedvfkqglasylhtfayqntiylnlwdhlqeavnnrsiqlpttvrdimnrwtlqm
gfpvitvdtstgtlsqehflldpdsnvtrpsefnyvwivpitsirdgrqqqdywlidvra
qndlfstsgnewvllnlnvtgyyrvnydeenwrkiqtqlqrdhsaipvinraqiindafn
lasahkvpvtlalnntlflieerqympweaalsslsyfklmfdrsevygpmknylkkqvt
plfihfrnntnnwreipenlmdqysevnaistacsngvpeceemvsglfkqwmenpnnnp
ihpnlrstvycnaiaqggeeewdfaweqfrnatlvneadklraalacskelwilnrylsy
tlnpdlirkqdatstiisitnnvigqglvwdfvqsnwkklfndygggsfsfsnliqavtr
rfsteyelqqleqfkkdneetgfgsgtraleqalektkanikwvkenkevvlqwftensk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6u7eB (B:)
ggrpdqskawnryrlpntlkpdsyrvtlrpyltpndrglyvfkgsstvrftckeatdvii
ihskklnytlsqghrvvlrgvggsqppdidktelvepteylvvhlkgslvkdsqyemdse
fegeladdlagfyrseymegnvrkvvattqmqaadarksfpcfdepamkaefnitlihpk
dltalsnmlpkgpstplpedpnwnvtefhttpkmstyllafivsefdyvekqasngvlir
iwarpsaiaaghgdyalnvtgpilnffaghydtpyplpksdqiglpdfnagamenwglvt
yrensllfdplsssssnkervvtviahelahqwfgnlvtiewwndlwlnegfasyveylg
adyaeptwnlkdlmvlndvyrvmavdalasshplstpaseintpaqiselfdaisyskga
svlrmlssflsedvfkqglasylhtfayqntiylnlwdhlqeavnnrsiqlpttvrdimn
rwtlqmgfpvitvdtstgtlsqehflldpdsnvtrpsefnyvwivpitsirdgrqqqdyw
lidvraqndlfstsgnewvllnlnvtgyyrvnydeenwrkiqtqlqrdhsaipvinraqi
indafnlasahkvpvtlalnntlflieerqympweaalsslsyfklmfdrsevygpmkny
lkkqvtplfihfrnntnnwreipenlmdqysevnaistacsngvpeceemvsglfkqwme
npnnnpihpnlrstvycnaiaqggeeewdfaweqfrnatlvneadklraalacskelwil
nrylsytlnpdlirkqdatstiisitnnvigqglvwdfvqsnwkklfndygggsfsfsnl
iqavtrrfsteyelqqleqfkkdneetgfgsgtraleqalektkanikwvkenkevvlqw
ftensk

    Sequence, based on observed residues (ATOM records): (download) 
    >6u7eB (B:)
skawnryrlpntlkpdsyrvtlrpyltpndrglyvfkgsstvrftckeatdviiihskkl
nytlsqghrvvlrgvggsqppdidktelvepteylvvhlkgslvkdsqyemdsefegela
ddlagfyrseymegnvrkvvattqmqaadarksfpcfdepamkaefnitlihpkdltals
nmlpkgpstplpedpnwnvtefhttpkmstyllafivsefdyvekqasngvliriwarps
aiaaghgdyalnvtgpilnffaghydtpyplpksdqiglpdfnagamenwglvtyrensl
lfdplsssssnkervvtviahelahqwfgnlvtiewwndlwlnegfasyveylgadyaep
twnlkdlmvlndvyrvmavdalasshplstpaseintpaqiselfdaisyskgasvlrml
ssflsedvfkqglasylhtfayqntiylnlwdhlqeavnnrsiqlpttvrdimnrwtlqm
gfpvitvdtstgtlsqehflldpdsnvtrpsefnyvwivpitsirdgrqqqdywlidvra
qndlfstsgnewvllnlnvtgyyrvnydeenwrkiqtqlqrdhsaipvinraqiindafn
lasahkvpvtlalnntlflieerqympweaalsslsyfklmfdrsevygpmknylkkqvt
plfihfrnntnnwreipenlmdqysevnaistacsngvpeceemvsglfkqwmenpnnnp
ihpnlrstvycnaiaqggeeewdfaweqfrnatlvneadklraalacskelwilnrylsy
tlnpdlirkqdatstiisitnnvigqglvwdfvqsnwkklfndygggsfsfsnliqavtr
rfsteyelqqleqfkkdneetgfgsgtraleqalektkanikwvkenkevvlqwftensk

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.