PDB entry 6s2k

View 6s2k on RCSB PDB site
Description: Human Menin in complex with AJ21
Class: oncoprotein
Keywords: oncoprotein
Deposited on 2019-06-21, released 2021-01-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-01-13, with a file datestamp of 2021-01-08.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Multiple endocrine neoplasia I, isoform CRA_b
    Species: Homo sapiens [TaxId:9606]
    Gene: MEN1, hCG_2017452
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s2ka1, d6s2ka2, d6s2ka3
  • Chain 'B':
    Compound: Multiple endocrine neoplasia I, isoform CRA_b
    Species: Homo sapiens [TaxId:9606]
    Gene: MEN1, hCG_2017452
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s2kb1, d6s2kb2, d6s2kb3
  • Heterogens: KTQ

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6s2kA (A:)
gamglkaaqktlfplrsiddvvrlfaaelgreepdlvllslvlgfvehflavnrviptnv
peltfqpspapdppggltyfpvadlsiiaalyarftaqirgavdlslypreggvssrelv
kkvsdviwnslsrsyfkdrahiqslfsfitgtkldssgvafavvgacqalglrdvhlals
edhawvvfgpngeqtaevtwhgkgnedrrgqtvnagvaerswlylkgsymrcdrkmevaf
mvcainpsidlhtdslellqlqqkllwllydlghlerypmalgnladleeleptpgrpdp
ltlyhkgiasaktyyrdehiypymylagyhcrnrnvrealqawadtatviqdynycrede
eiykeffevandvipnllkeaaslleageerpgeqsqgtqsqgsalqdpecfahllrfyd
gickweegsptpvlhvgwatflvqslgrfegqvrqkvrivsgtvagtargpeggstaqvp
apaaspppegpvltfqsekmkgmkellvatkinssaiklqltaqsq

    Sequence, based on observed residues (ATOM records): (download) 
    >6s2kA (A:)
lkaaqktlfplrsiddvvrlfaaelgreepdlvllslvlgfvehflavnrvipspapdpp
ggltyfpvadlsiiaalyarftaqirgavdlslypreggvssrelvkkvsdviwnslsrs
yfkdrahiqslfsfitgtkldssgvafavvgacqalglrdvhlalsedhawvvfgpngeq
taevtwhgkgnedrrgqtvnagvaerswlylkgsymrcdrkmevafmvcainpsidlhtd
slellqlqqkllwllydlghlerypmalgnladleeleptpgrpdpltlyhkgiasakty
yrdehiypymylagyhcrnrnvrealqawadtatviqdynycredeeiykeffevandvi
pnllkeaaslleasalqdpecfahllrfydgickweegsptpvlhvgwatflvqslgrfe
gqvrqkvrivsgtvgpvltfqsekmkgmkellvatkinssaiklqlta

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6s2kB (B:)
gamglkaaqktlfplrsiddvvrlfaaelgreepdlvllslvlgfvehflavnrviptnv
peltfqpspapdppggltyfpvadlsiiaalyarftaqirgavdlslypreggvssrelv
kkvsdviwnslsrsyfkdrahiqslfsfitgtkldssgvafavvgacqalglrdvhlals
edhawvvfgpngeqtaevtwhgkgnedrrgqtvnagvaerswlylkgsymrcdrkmevaf
mvcainpsidlhtdslellqlqqkllwllydlghlerypmalgnladleeleptpgrpdp
ltlyhkgiasaktyyrdehiypymylagyhcrnrnvrealqawadtatviqdynycrede
eiykeffevandvipnllkeaaslleageerpgeqsqgtqsqgsalqdpecfahllrfyd
gickweegsptpvlhvgwatflvqslgrfegqvrqkvrivsgtvagtargpeggstaqvp
apaaspppegpvltfqsekmkgmkellvatkinssaiklqltaqsq

    Sequence, based on observed residues (ATOM records): (download) 
    >6s2kB (B:)
lkaaqktlfplrsiddvvrlfaaelgreepdlvllslvlgfvehflavnrvpapdppggl
tyfpvadlsiiaalyarftaqirgavdlslypreggvssrelvkkvsdviwnslsrsyfk
drahiqslfsfitgtkldssgvafavvgacqalglrdvhlalsedhawvvfgpngeqtae
vtwhgkgnedrrgqtvnagvaerswlylkgsymrcdrkmevafmvcainpsidlhtdsle
llqlqqkllwllydlghlerypmalgnladleeleptpgrpdpltlyhkgiasaktyyrd
ehiypymylagyhcrnrnvrealqawadtatviqdynycredeeiykeffevandvipnl
lkeaaslleasalqdpecfahllrfydgickweegsptpvlhvgwatflvqslgrfegqv
rqkvrivsggpvltfqsekmkgmkellvatkinssaiklqlta