PDB entry 6req

View 6req on RCSB PDB site
Description: methylmalonyl-coa mutase, 3-carboxypropyl-coa inhibitor complex
Class: isomerase
Keywords: isomerase, mutase, intramolecular transferase
Deposited on 1998-09-03, released 1999-09-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-10-24, with a file datestamp of 2012-10-19.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.216
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (methylmalonyl-coa mutase)
    Species: Propionibacterium freudenreichii [TaxId:1752]
    Gene: mutB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6reqa1, d6reqa2
  • Chain 'B':
    Compound: protein (methylmalonyl-coa mutase)
    Species: Propionibacterium freudenreichii [TaxId:1752]
    Gene: MUTA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11652 (Start-636)
      • see remark 999 (201)
      • see remark 999 (328-329)
    Domains in SCOPe 2.07: d6reqb1, d6reqb2
  • Chain 'C':
    Compound: protein (methylmalonyl-coa mutase)
    Species: Propionibacterium freudenreichii [TaxId:1752]
    Gene: mutB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6reqc1, d6reqc2
  • Chain 'D':
    Compound: protein (methylmalonyl-coa mutase)
    Species: Propionibacterium freudenreichii [TaxId:1752]
    Gene: MUTA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11652 (Start-636)
      • see remark 999 (201)
      • see remark 999 (328-329)
    Domains in SCOPe 2.07: d6reqd1, d6reqd2
  • Heterogens: 3CP, B12, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6reqA (A:)
stlprfdsvdlgnapvpadaarrfeelaakagtgeawetaeqipvgtlfnedvykdmdwl
dtyagippfvhgpyatmyafrpwtirqyagfstakesnafyrrnlaagqkglsvafdlpt
hrgydsdnprvagdvgmagvaidsiydmrelfagipldqmsvsmtmngavlpilalyvvt
aeeqgvkpeqlagtiqndilkefmvrntyiyppqpsmriiseifaytsanmpkwnsisis
gyhmqeagatadiemaytladgvdyiragesvglnvdqfaprlsffwgigmnffmevakl
raarmlwaklvhqfgpknpksmslrthsqtsgwsltaqdvynnvvrtcieamaatqghtq
slhtnsldeaialptdfsariarntqlflqqesgttrvidpwsgsayveeltwdlarkaw
ghiqevekvggmakaiekgipkmrieeaaartqaridsgrqpligvnkyrleheppldvl
kvdnstvlaeqkaklvklraerdpekvkaaldkitwaagnpddkdpdrnllklcidagra
matvgemsdalekvfgrytaqirtisgvyskevkntpeveearelveefeqaegrrpril
lakmgqdghdrgqkviatayadlgfdvdvgplfqtpeetarqaveadvhvvgvsslaggh
ltlvpalrkeldklgrpdilitvggvipeqdfdelrkdgaveiytpgtvipesaislvkk
lraslda

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6reqB (B:)
sstdqgtnpadtddltpttlslagdfpkateeqwerevekvlnrgrppekqltfaeclkr
ltvhtvdgidivpmyrpkdapkklgypgvapftrgttvrngdmdawdvralhedpdekft
rkaileglergvtslllrvdpdaiapehldevlsdvllemtkvevfsrydqgaaaealvs
vyersdkpakdlalnlgldpigfaalqgtepdltvlgdwvrrlakfspdsravtidaniy
hnagagdvaelawalatgaeyvralveqgftateafdtinfrvtathdqfltiarlralr
eawarigevfgvdedkrgarqnaitswreltredpyvnilrgsiatfsasvggaesittl
pftqalglpeddfplriarntgivlaeevnigrvndpaggsyyvesltrsladaawkefq
eveklggmskavmtehvtkvldacnaerakrlanrkqpitavsefpmigarsietkpfpa
aparkglawhrdsevfeqlmdrstsvserpkvflaclgtrrdfggregfsspvwhiagid
tpqveggttaeiveafkksgaqvadlcssakvyaqqglevakalkaagakalylsgafke
fgddaaeaeklidgrlfmgmdvvdtlsstldilgvak

    Sequence, based on observed residues (ATOM records): (download) 
    >6reqB (B:)
tlslagdfpkateeqwerevekvlnrgrppekqltfaeclkrltvhtvdgidivpmyrpk
dapkklgypgvapftrgttvrngdmdawdvralhedpdekftrkaileglergvtslllr
vdpdaiapehldevlsdvllemtkvevfsrydqgaaaealvsvyersdkpakdlalnlgl
dpigfaalqgtepdltvlgdwvrrlakfspdsravtidaniyhnagagdvaelawalatg
aeyvralveqgftateafdtinfrvtathdqfltiarlralreawarigevfgvdedkrg
arqnaitswreltredpyvnilrgsiatfsasvggaesittlpftqalglpeddfplria
rntgivlaeevnigrvndpaggsyyvesltrsladaawkefqeveklggmskavmtehvt
kvldacnaerakrlanrkqpitavsefpmigarsietkpfpaaparkglawhrdsevfeq
lmdrstsvserpkvflaclgtrrdfggregfsspvwhiagidtpqveggttaeiveafkk
sgaqvadlcssakvyaqqglevakalkaagakalylsgafkefgddaaeaeklidgrlfm
gmdvvdtlsstldilgvak

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6reqC (C:)
stlprfdsvdlgnapvpadaarrfeelaakagtgeawetaeqipvgtlfnedvykdmdwl
dtyagippfvhgpyatmyafrpwtirqyagfstakesnafyrrnlaagqkglsvafdlpt
hrgydsdnprvagdvgmagvaidsiydmrelfagipldqmsvsmtmngavlpilalyvvt
aeeqgvkpeqlagtiqndilkefmvrntyiyppqpsmriiseifaytsanmpkwnsisis
gyhmqeagatadiemaytladgvdyiragesvglnvdqfaprlsffwgigmnffmevakl
raarmlwaklvhqfgpknpksmslrthsqtsgwsltaqdvynnvvrtcieamaatqghtq
slhtnsldeaialptdfsariarntqlflqqesgttrvidpwsgsayveeltwdlarkaw
ghiqevekvggmakaiekgipkmrieeaaartqaridsgrqpligvnkyrleheppldvl
kvdnstvlaeqkaklvklraerdpekvkaaldkitwaagnpddkdpdrnllklcidagra
matvgemsdalekvfgrytaqirtisgvyskevkntpeveearelveefeqaegrrpril
lakmgqdghdrgqkviatayadlgfdvdvgplfqtpeetarqaveadvhvvgvsslaggh
ltlvpalrkeldklgrpdilitvggvipeqdfdelrkdgaveiytpgtvipesaislvkk
lraslda

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6reqD (D:)
sstdqgtnpadtddltpttlslagdfpkateeqwerevekvlnrgrppekqltfaeclkr
ltvhtvdgidivpmyrpkdapkklgypgvapftrgttvrngdmdawdvralhedpdekft
rkaileglergvtslllrvdpdaiapehldevlsdvllemtkvevfsrydqgaaaealvs
vyersdkpakdlalnlgldpigfaalqgtepdltvlgdwvrrlakfspdsravtidaniy
hnagagdvaelawalatgaeyvralveqgftateafdtinfrvtathdqfltiarlralr
eawarigevfgvdedkrgarqnaitswreltredpyvnilrgsiatfsasvggaesittl
pftqalglpeddfplriarntgivlaeevnigrvndpaggsyyvesltrsladaawkefq
eveklggmskavmtehvtkvldacnaerakrlanrkqpitavsefpmigarsietkpfpa
aparkglawhrdsevfeqlmdrstsvserpkvflaclgtrrdfggregfsspvwhiagid
tpqveggttaeiveafkksgaqvadlcssakvyaqqglevakalkaagakalylsgafke
fgddaaeaeklidgrlfmgmdvvdtlsstldilgvak

    Sequence, based on observed residues (ATOM records): (download) 
    >6reqD (D:)
tlslagdfpkateeqwerevekvlnrgrppekqltfaeclkrltvhtvdgidivpmyrpk
dapkklgypgvapftrgttvrngdmdawdvralhedpdekftrkaileglergvtslllr
vdpdaiapehldevlsdvllemtkvevfsrydqgaaaealvsvyersdkpakdlalnlgl
dpigfaalqgtepdltvlgdwvrrlakfspdsravtidaniyhnagagdvaelawalatg
aeyvralveqgftateafdtinfrvtathdqfltiarlralreawarigevfgvdedkrg
arqnaitswreltredpyvnilrgsiatfsasvggaesittlpftqalglpeddfplria
rntgivlaeevnigrvndpaggsyyvesltrsladaawkefqeveklggmskavmtehvt
kvldacnaerakrlanrkqpitavsefpmigarsietkpfpaaparkglawhrdsevfeq
lmdrstsvserpkvflaclgtrrdfggregfsspvwhiagidtpqveggttaeiveafkk
sgaqvadlcssakvyaqqglevakalkaagakalylsgafkefgddaaeaeklidgrlfm
gmdvvdtlsstldilgvak