PDB entry 6nmo

View 6nmo on RCSB PDB site
Description: Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF) Burkholderia pseudomallei in compomplex with ligand SR-4.
Class: lyase
Keywords: SSGCID, Burkholderia pseudomallei, 2-C-methyl-D-erythritol 2, 4-cyclodiphosphate synthase, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, LYASE
Deposited on 2019-01-11, released 2020-01-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-01-15, with a file datestamp of 2020-01-10.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: N/A
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Burkholderia pseudomallei (strain 1710b) [TaxId:320372]
    Gene: ispF, BURPS1710b_2511
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6nmoa_
  • Chain 'B':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Burkholderia pseudomallei (strain 1710b) [TaxId:320372]
    Gene: ispF, BURPS1710b_2511
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6nmob_
  • Chain 'C':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Burkholderia pseudomallei (strain 1710b) [TaxId:320372]
    Gene: ispF, BURPS1710b_2511
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q3JRA0 (1-End)
      • expression tag (0)
    Domains in SCOPe 2.07: d6nmoc1, d6nmoc2
  • Heterogens: ZN, DMS, MLI, EDO, QMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6nmoA (A:)
smdfrigqgydvhqlvpgrpliiggvtipyergllghsdadvllhaitdalfgaaalgdi
grhfsdtdprfkgadsrallrecasrvaqagfairnvdstiiaqapklaphidamrania
adldlpldrvnvkaktneklgylgrgegieaqaaalvvreaaa

    Sequence, based on observed residues (ATOM records): (download) 
    >6nmoA (A:)
mdfrigqgydvhqlvpgrpliiggvtipyergllghsdadvllhaitdalfgaaalgdig
rhfsdtdprfkgadsrallrecasrvaqagfairnvdstiiaqapklaphidamraniaa
dldlpldrvnvkaktneklgylgrgegieaqaaalvvre

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6nmoB (B:)
smdfrigqgydvhqlvpgrpliiggvtipyergllghsdadvllhaitdalfgaaalgdi
grhfsdtdprfkgadsrallrecasrvaqagfairnvdstiiaqapklaphidamrania
adldlpldrvnvkaktneklgylgrgegieaqaaalvvreaaa

    Sequence, based on observed residues (ATOM records): (download) 
    >6nmoB (B:)
mdfrigqgydvhqlvpgrpliiggvtipyergllghsdadvllhaitdalfgaaalgdig
rhfsdtdprfkgadsrallrecasrvaqagfairnvdstiiaqapklaphidamraniaa
dldlpldrvnvkaktneklgylgrgegieaqaaalvvre

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6nmoC (C:)
smdfrigqgydvhqlvpgrpliiggvtipyergllghsdadvllhaitdalfgaaalgdi
grhfsdtdprfkgadsrallrecasrvaqagfairnvdstiiaqapklaphidamrania
adldlpldrvnvkaktneklgylgrgegieaqaaalvvreaaa

    Sequence, based on observed residues (ATOM records): (download) 
    >6nmoC (C:)
smdfrigqgydvhqlvpgrpliiggvtipyergllghsdadvllhaitdalfgaaalgdi
grhfsdtdprfkgadsrallrecasrvaqagfairnvdstiiaqapklaphidamrania
adldlpldrvnvkaktneklgylgrgegieaqaaalvvre