PDB entry 6jl6

View 6jl6 on RCSB PDB site
Description: Crystal structure of aspartate transcarbamoylase from Trypanosoma cruzi in complex with phosphate (Pi).
Class: transferase
Keywords: ATCase, Pyrimidine metabolism, TRANSFERASE
Deposited on 2019-03-04, released 2020-03-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-03-04, with a file datestamp of 2020-02-28.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15636 (1-326)
      • expression tag (0)
    Domains in SCOPe 2.07: d6jl6a1, d6jl6a2, d6jl6a3
  • Chain 'B':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15636 (1-326)
      • expression tag (0)
    Domains in SCOPe 2.07: d6jl6b1, d6jl6b2, d6jl6b3
  • Chain 'C':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6jl6c1, d6jl6c2
  • Chain 'D':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15636 (1-326)
      • expression tag (0)
    Domains in SCOPe 2.07: d6jl6d1, d6jl6d2, d6jl6d3
  • Chain 'E':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15636 (1-326)
      • expression tag (0)
    Domains in SCOPe 2.07: d6jl6e1, d6jl6e2, d6jl6e3
  • Chain 'F':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15636 (1-326)
      • expression tag (0)
    Domains in SCOPe 2.07: d6jl6f1, d6jl6f2, d6jl6f3
  • Heterogens: ASP, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6jl6A (A:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqda
ieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsl
lkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvly
ttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttvd
adpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jl6A (A:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkvekgetladtirtldsysdvlvmrhprqdaieeal
svaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsllkllv
rnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvlyttrlq
kkaditidaarmrlakekmivmhplprndelsttvdadpraayfrqmrygmfmrmailws
vla

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6jl6B (B:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqda
ieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsl
lkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvly
ttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttvd
adpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jl6B (B:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkveetladtirtldsysdvlvmrhprqdaieealsv
aqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsllkllvrn
fsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvlyttrlkad
itidaarmrlakekmivmhplprndelsttvdadpraayfrqmrygmfmrmailwsvla

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6jl6C (C:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqda
ieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsl
lkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvly
ttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttvd
adpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jl6C (C:)
lelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplffed
ssrtfssfcaamirlggsvvnfkveetladtirtldsysdvlvmrhprqdaieealsvaq
hpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsllkllvrnfs
ikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvlyttrlqkerf
mastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttvdadpraayfr
qmrygmfmrmailwsvla

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6jl6D (D:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqda
ieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsl
lkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvly
ttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttvd
adpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jl6D (D:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkvetladtirtldsysdvlvmrhprqdaieealsva
qhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsllkllvrnf
sikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvlyttrlqkaa
kaditidaarmrlakekmivmhplprndelsttvdadpraayfrqmrygmfmrmailwsv
la

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6jl6E (E:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqda
ieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsl
lkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvly
ttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttvd
adpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jl6E (E:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqda
ieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsl
lkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvly
ttrlddaaalqsfaakaditidaarmrlakekmivmhplprndelsttvdadpraayfrq
mrygmfmrmailwsvla

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6jl6F (F:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqda
ieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsl
lkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvly
ttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttvd
adpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jl6F (F:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkvegetladtirtldsysdvlvmrhprqdaieeals
vaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsllkllvr
nfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvlyttrlqk
erfaaalqsfaakaditidaarmrlakekmivmhplprndelsttvdadpraayfrqmry
gmfmrmailwsvla