PDB entry 6i6c

View 6i6c on RCSB PDB site
Description: sepiapterin reductase in complex with compound 2
Class: oxidoreductase
Keywords: sepiapterin-reductase, oxidoreductase, proteros biostructures gmbh
Deposited on 2018-11-15, released 2019-07-10
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-07-10, with a file datestamp of 2019-07-05.
Experiment type: XRAY
Resolution: 1.72 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: sepiapterin reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: SPR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35270 (15-End)
      • expression tag (7-14)
    Domains in SCOPe 2.07: d6i6ca1, d6i6ca2
  • Chain 'B':
    Compound: sepiapterin reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: SPR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6i6cb_
  • Heterogens: NAP, H4H, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6i6cA (A:)
mghhhhhhenlyfqgmegglgravclltgasrgfgrtlapllasllspgsvlvlsarnde
alrqleaelgaersglrvvrvpadlgaeaglqqllgalrelprpkglqrlllinnagslg
dvskgfvdlsdstqvnnywalnltsmlcltssvlkafpdspglnrtvvnisslcalqpfk
gwalycagkaardmlfqvlaleepnvrvlnyapgpldtdmqqlaretsvdpdmrkglqel
kakgklvdckvsaqkllsllekdefksgahvdfydk

    Sequence, based on observed residues (ATOM records): (download) 
    >6i6cA (A:)
henlyfqgmegglgravclltgasrgfgrtlapllasllspgsvlvlsarndealrqlea
elgaeglrvvrvpadlgaeaglqqllgalrelprpkglqrlllinnagslgdvskgfvdl
sdstqvnnywalnltsmlcltssvlkafpdspglnrtvvnisslcalqpfkgwalycagk
aardmlfqvlaleepnvrvlnyapgpldtdmqqlaretsvdpdmrkglqelkakgklvdc
kvsaqkllsllekdefksgahvdfyd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6i6cB (B:)
mghhhhhhenlyfqgmegglgravclltgasrgfgrtlapllasllspgsvlvlsarnde
alrqleaelgaersglrvvrvpadlgaeaglqqllgalrelprpkglqrlllinnagslg
dvskgfvdlsdstqvnnywalnltsmlcltssvlkafpdspglnrtvvnisslcalqpfk
gwalycagkaardmlfqvlaleepnvrvlnyapgpldtdmqqlaretsvdpdmrkglqel
kakgklvdckvsaqkllsllekdefksgahvdfydk

    Sequence, based on observed residues (ATOM records): (download) 
    >6i6cB (B:)
glgravclltgasrgfgrtlapllasllspgsvlvlsarndealrqleaelgaersglrv
vrvpadlgaeaglqqllgalrelprpkglqrlllinnagslgdvskgfvdlsdstqvnny
walnltsmlcltssvlkafpdspglnrtvvnisslcalqpfkgwalycagkaardmlfqv
laleepnvrvlnyapgpldtdmqqlaretsvdpdmrkglqelkakgklvdckvsaqklls
llekdefksgahvdfyd