PDB entry 6fbp

View 6fbp on RCSB PDB site
Description: Human Methionine Adenosyltransferase II mutant (S114A) in P22121 crystal form
Class: transferase
Keywords: transferase
Deposited on 2017-12-19, released 2019-01-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-08-14, with a file datestamp of 2019-08-09.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: S-adenosylmethionine synthase isoform type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAT2A, AMS2, MATA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P31153 (Start-394)
      • conflict (113)
    Domains in SCOPe 2.08: d6fbpa1, d6fbpa2, d6fbpa3
  • Chain 'B':
    Compound: S-adenosylmethionine synthase isoform type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAT2A, AMS2, MATA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P31153 (Start-394)
      • conflict (113)
    Domains in SCOPe 2.08: d6fbpb1, d6fbpb2, d6fbpb3
  • Heterogens: ADN, K, MG, PPK, PG4, ACT, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6fbpA (A:)
mngqlngfheafieegtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetva
ktgmillageitsraavdyqkvvreavkhigyddsskgfdyktcnvlvaleqqapdiaqg
vhldrneedigagdqglmfgyatdeteecmpltivlahklnaklaelrrngtlpwlrpds
ktqvtvqymqdrgavlpirvhtivisvqhdeevcldemrdalkekvikavvpakyldedt
iyhlqpsgrfviggpqgdagltgrkiivdtyggwgahgggafsgkdytkvdrsaayaarw
vakslvkgglcrrvlvqvsyaigvshplsisifhygtsqkserelleivkknfdlrpgvi
vrdldlkkpiyqrtaayghfgrdsfpwevpkklky

    Sequence, based on observed residues (ATOM records): (download) 
    >6fbpA (A:)
gtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetvaktgmillageitsra
avdyqkvvreavkhigyddsskgfdyktcnvlvaleqqapdiaqgvhldrneedigagdq
glmfgyatdeteecmpltivlahklnaklaelrrngtlpwlrpdsktqvtvqymqdrgav
lpirvhtivisvqhdeevcldemrdalkekvikavvpakyldedtiyhlqpsgrfviggp
qgdagltgrkiivdtyggwgahgggafsgkdytkvdrsaayaarwvakslvkgglcrrvl
vqvsyaigvshplsisifhygtsqkserelleivkknfdlrpgvivrdldlkkpiyqrta
ayghfgrdsfpwevpkklky

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6fbpB (B:)
mngqlngfheafieegtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetva
ktgmillageitsraavdyqkvvreavkhigyddsskgfdyktcnvlvaleqqapdiaqg
vhldrneedigagdqglmfgyatdeteecmpltivlahklnaklaelrrngtlpwlrpds
ktqvtvqymqdrgavlpirvhtivisvqhdeevcldemrdalkekvikavvpakyldedt
iyhlqpsgrfviggpqgdagltgrkiivdtyggwgahgggafsgkdytkvdrsaayaarw
vakslvkgglcrrvlvqvsyaigvshplsisifhygtsqkserelleivkknfdlrpgvi
vrdldlkkpiyqrtaayghfgrdsfpwevpkklky

    Sequence, based on observed residues (ATOM records): (download) 
    >6fbpB (B:)
gtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetvaktgmillageitsra
avdyqkvvreavkhigyddsskgfdyktcnvlvaleqqapdiaqgvhldragdqglmfgy
atdeteecmpltivlahklnaklaelrrngtlpwlrpdsktqvtvqymqdrgavlpirvh
tivisvqhdeevcldemrdalkekvikavvpakyldedtiyhlqpsgrfviggpqgdagl
tgrkiivdtyggwgahgggafsgkdytkvdrsaayaarwvakslvkgglcrrvlvqvsya
igvshplsisifhygtsqkserelleivkknfdlrpgvivrdldlkkpiyqrtaayghfg
rdsfpwevpkklky