PDB entry 6c8q

View 6c8q on RCSB PDB site
Description: Crystal structure of NAD synthetase (NadE) from Enterococcus faecalis in complex with NAD+
Class: transferase
Keywords: NAD, NadE, AMIDOTRANSFERASE, NH3 DEPENDENT, ATP PYROPHOSPHATASE, LIGASE, structural genomics, NIAID, National Institute of Allergy and Infectious Diseases, CSGID, Center for Structural Genomics of Infectious Diseases, TRANSFERASE
Deposited on 2018-01-25, released 2018-02-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-02-14, with a file datestamp of 2018-02-09.
Experiment type: XRAY
Resolution: 2.58 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: nh(3)-dependent nad(+) synthetase
    Species: Enterococcus faecalis V583 [TaxId:226185]
    Gene: nadE, EF_2625
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c8qa_
  • Chain 'B':
    Compound: nh(3)-dependent nad(+) synthetase
    Species: Enterococcus faecalis V583 [TaxId:226185]
    Gene: nadE, EF_2625
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c8qb_
  • Chain 'C':
    Compound: nh(3)-dependent nad(+) synthetase
    Species: Enterococcus faecalis V583 [TaxId:226185]
    Gene: nadE, EF_2625
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c8qc_
  • Chain 'D':
    Compound: nh(3)-dependent nad(+) synthetase
    Species: Enterococcus faecalis V583 [TaxId:226185]
    Gene: nadE, EF_2625
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c8qd_
  • Chain 'E':
    Compound: nh(3)-dependent nad(+) synthetase
    Species: Enterococcus faecalis V583 [TaxId:226185]
    Gene: nadE, EF_2625
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c8qe_
  • Chain 'F':
    Compound: nh(3)-dependent nad(+) synthetase
    Species: Enterococcus faecalis V583 [TaxId:226185]
    Gene: nadE, EF_2625
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c8qf_
  • Chain 'G':
    Compound: nh(3)-dependent nad(+) synthetase
    Species: Enterococcus faecalis V583 [TaxId:226185]
    Gene: nadE, EF_2625
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c8qg_
  • Chain 'H':
    Compound: nh(3)-dependent nad(+) synthetase
    Species: Enterococcus faecalis V583 [TaxId:226185]
    Gene: nadE, EF_2625
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c8qh_
  • Heterogens: NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6c8qA (A:)
mttlqekiiqelgvlptidpkeevrksidflkayltkhpflktfvlgisggqdstlagrl
aqlamtemreetgdmsyqfiairlpygeqadeadaqaalafiqpdvslrvdikpavdamv
gslenagvqisdfnkgnmkarqrmitqyavagenagavigtdhaaenvtafftkygdgga
dilplfrlnkrqgkallkelgapealylkiptadleddkplvadevalgvtydaiddyle
gkkvsetdqqtienwykkgqhkrhlpitifddfwk

    Sequence, based on observed residues (ATOM records): (download) 
    >6c8qA (A:)
ttlqekiiqelgvlptidpkeevrksidflkayltkhpflktfvlgisggqdstlagrla
qlamtemreetgdmsyqfiairlpygeqadeadaqaalafiqpdvslrvdikpavdamvg
slenagvqisdfnkgnmkarqrmitqyavagenagavigtdhaaenvtafftkygdggad
ilplfrlnkrqgkallkelgapealylkeddkplvadevalgvtydaiddylegkkvset
dqqtienwykkgqhkrhlpitifddfwk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6c8qB (B:)
mttlqekiiqelgvlptidpkeevrksidflkayltkhpflktfvlgisggqdstlagrl
aqlamtemreetgdmsyqfiairlpygeqadeadaqaalafiqpdvslrvdikpavdamv
gslenagvqisdfnkgnmkarqrmitqyavagenagavigtdhaaenvtafftkygdgga
dilplfrlnkrqgkallkelgapealylkiptadleddkplvadevalgvtydaiddyle
gkkvsetdqqtienwykkgqhkrhlpitifddfwk

    Sequence, based on observed residues (ATOM records): (download) 
    >6c8qB (B:)
mttlqekiiqelgvlptidpkeevrksidflkayltkhpflktfvlgisggqdstlagrl
aqlamtemreetgdmsyqfiairlpygeqadeadaqaalafiqpdvslrvdikpavdamv
gslenagvqisdfnkgnmkarqrmitqyavagenagavigtdhaaenvtafftkygdgga
dilplfrlnkrqgkallkelgapealylkkplvadevalgvtydaiddylegkkvsetdq
qtienwykkgqhkrhlpitifddfwk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6c8qC (C:)
mttlqekiiqelgvlptidpkeevrksidflkayltkhpflktfvlgisggqdstlagrl
aqlamtemreetgdmsyqfiairlpygeqadeadaqaalafiqpdvslrvdikpavdamv
gslenagvqisdfnkgnmkarqrmitqyavagenagavigtdhaaenvtafftkygdgga
dilplfrlnkrqgkallkelgapealylkiptadleddkplvadevalgvtydaiddyle
gkkvsetdqqtienwykkgqhkrhlpitifddfwk

    Sequence, based on observed residues (ATOM records): (download) 
    >6c8qC (C:)
mttlqekiiqelgvlptidpkeevrksidflkayltkhpflktfvlgisggqdstlagrl
aqlamtemreetgdmsyqfiairlpygeqadeadaqaalafiqpdvslrvdikpavdamv
gslenagvqisdfnkgnmkarqrmitqyavagenagavigtdhaaenvtafftkygdgga
dilplfrlnkrqgkallkelgapealylkplvadevalgvtydaiddylegkkvsetdqq
tienwykkgqhkrhlpitifddfwk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6c8qD (D:)
mttlqekiiqelgvlptidpkeevrksidflkayltkhpflktfvlgisggqdstlagrl
aqlamtemreetgdmsyqfiairlpygeqadeadaqaalafiqpdvslrvdikpavdamv
gslenagvqisdfnkgnmkarqrmitqyavagenagavigtdhaaenvtafftkygdgga
dilplfrlnkrqgkallkelgapealylkiptadleddkplvadevalgvtydaiddyle
gkkvsetdqqtienwykkgqhkrhlpitifddfwk

    Sequence, based on observed residues (ATOM records): (download) 
    >6c8qD (D:)
ttlqekiiqelgvlptidpkeevrksidflkayltkhpflktfvlgisggqdstlagrla
qlamtemreetgdmsyqfiairlpygeqadeadaqaalafiqpdvslrvdikpavdamvg
slenagvqisdfnkgnmkarqrmitqyavagenagavigtdhaaenvtafftkygdggad
ilplfrlnkrqgkallkelgapealylkplvadevalgvtydaiddylegkkvsetdqqt
ienwykkgqhkrhlpitifddfwk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6c8qE (E:)
mttlqekiiqelgvlptidpkeevrksidflkayltkhpflktfvlgisggqdstlagrl
aqlamtemreetgdmsyqfiairlpygeqadeadaqaalafiqpdvslrvdikpavdamv
gslenagvqisdfnkgnmkarqrmitqyavagenagavigtdhaaenvtafftkygdgga
dilplfrlnkrqgkallkelgapealylkiptadleddkplvadevalgvtydaiddyle
gkkvsetdqqtienwykkgqhkrhlpitifddfwk

    Sequence, based on observed residues (ATOM records): (download) 
    >6c8qE (E:)
mttlqekiiqelgvlptidpkeevrksidflkayltkhpflktfvlgisggqdstlagrl
aqlamtemreetgdmsyqfiairlpygeqadeadaqaalafiqpdvslrvdikpavdamv
gslenagvqisdfnkgnmkarqrmitqyavagenagavigtdhaaenvtafftkygdgga
dilplfrlnkrqgkallkelgapealyllvadevalgvtydaiddylegkkvsetdqqti
enwykkgqhkrhlpitifddfwk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6c8qF (F:)
mttlqekiiqelgvlptidpkeevrksidflkayltkhpflktfvlgisggqdstlagrl
aqlamtemreetgdmsyqfiairlpygeqadeadaqaalafiqpdvslrvdikpavdamv
gslenagvqisdfnkgnmkarqrmitqyavagenagavigtdhaaenvtafftkygdgga
dilplfrlnkrqgkallkelgapealylkiptadleddkplvadevalgvtydaiddyle
gkkvsetdqqtienwykkgqhkrhlpitifddfwk

    Sequence, based on observed residues (ATOM records): (download) 
    >6c8qF (F:)
mttlqekiiqelgvlptidpkeevrksidflkayltkhpflktfvlgisggqdstlagrl
aqlamtemreetgdmsyqfiairlpygeqadeadaqaalafiqpdvslrvdikpavdamv
gslenagvqisdfnkgnmkarqrmitqyavagenagavigtdhaaenvtafftkygdgga
dilplfrlnkrqgkallkelgapealylplvadevalgvtydaiddylegkkvsetdqqt
ienwykkgqhkrhlpitifddfwk

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6c8qG (G:)
mttlqekiiqelgvlptidpkeevrksidflkayltkhpflktfvlgisggqdstlagrl
aqlamtemreetgdmsyqfiairlpygeqadeadaqaalafiqpdvslrvdikpavdamv
gslenagvqisdfnkgnmkarqrmitqyavagenagavigtdhaaenvtafftkygdgga
dilplfrlnkrqgkallkelgapealylkiptadleddkplvadevalgvtydaiddyle
gkkvsetdqqtienwykkgqhkrhlpitifddfwk

    Sequence, based on observed residues (ATOM records): (download) 
    >6c8qG (G:)
ttlqekiiqelgvlptidpkeevrksidflkayltkhpflktfvlgisggqdstlagrla
qlamtemreetgdmsyqfiairlpygeqadeadaqaalafiqpdvslrvdikpavdamvg
slenagvqisdfnkgnmkarqrmitqyavagenagavigtdhaaenvtafftkygdggad
ilplfrlnkrqgkallkelgapealylkkplvadevalgvtydaiddylegkkvsetdqq
tienwykkgqhkrhlpitifddfwk

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6c8qH (H:)
mttlqekiiqelgvlptidpkeevrksidflkayltkhpflktfvlgisggqdstlagrl
aqlamtemreetgdmsyqfiairlpygeqadeadaqaalafiqpdvslrvdikpavdamv
gslenagvqisdfnkgnmkarqrmitqyavagenagavigtdhaaenvtafftkygdgga
dilplfrlnkrqgkallkelgapealylkiptadleddkplvadevalgvtydaiddyle
gkkvsetdqqtienwykkgqhkrhlpitifddfwk

    Sequence, based on observed residues (ATOM records): (download) 
    >6c8qH (H:)
ttlqekiiqelgvlptidpkeevrksidflkayltkhpflktfvlgisggqdstlagrla
qlamtemreetgdmsyqfiairlpygeqadeadaqaalafiqpdvslrvdikpavdamvg
slenagvqisdfnkgnmkarqrmitqyavagenagavigtdhaaenvtafftkygdggad
ilplfrlnkrqgkallkelgapealylkipkplvadevalgvtydaiddylegkkvsetd
qqtienwykkgqhkrhlpitifddfwk