PDB entry 6c3u
View 6c3u on RCSB PDB site
Description: Crystal structure of Klebsiella pneumoniae fosfomycin resistance protein (FosAKP) with inhibitor (ANY2) bound
Class: transferase/inhibitor
Keywords: fosfomycin, FosA, FosAKP, glutathione S-transferase, ANY2, TRANSFERASE, TRANSFERASE-INHIBITOR complex
Deposited on
2018-01-10, released
2018-12-26
The last revision prior to the SCOPe 2.07 freeze date was dated
2018-12-26, with a file datestamp of
2018-12-21.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.35
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: FosA family fosfomycin resistance glutathione transferase
Species: Klebsiella pneumoniae [TaxId:573]
Gene: AGG09_10885, B8011_01255, BL102_0004085, CEO55_05040
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d6c3ua_ - Chain 'B':
Compound: FosA family fosfomycin resistance glutathione transferase
Species: Klebsiella pneumoniae [TaxId:573]
Gene: AGG09_10885, B8011_01255, BL102_0004085, CEO55_05040
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d6c3ub_ - Chain 'C':
Compound: FosA family fosfomycin resistance glutathione transferase
Species: Klebsiella pneumoniae [TaxId:573]
Gene: AGG09_10885, B8011_01255, BL102_0004085, CEO55_05040
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d6c3uc_ - Chain 'D':
Compound: FosA family fosfomycin resistance glutathione transferase
Species: Klebsiella pneumoniae [TaxId:573]
Gene: AGG09_10885, B8011_01255, BL102_0004085, CEO55_05040
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d6c3ud_ - Heterogens: NY2, MN, GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6c3uA (A:)
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eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffeqhhhhhh
Sequence, based on observed residues (ATOM records): (download)
>6c3uA (A:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffe
- Chain 'B':
Sequence, based on SEQRES records: (download)
>6c3uB (B:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffeqhhhhhh
Sequence, based on observed residues (ATOM records): (download)
>6c3uB (B:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffe
- Chain 'C':
Sequence, based on SEQRES records: (download)
>6c3uC (C:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffeqhhhhhh
Sequence, based on observed residues (ATOM records): (download)
>6c3uC (C:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffe
- Chain 'D':
Sequence, based on SEQRES records: (download)
>6c3uD (D:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffeqhhhhhh
Sequence, based on observed residues (ATOM records): (download)
>6c3uD (D:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvff