PDB entry 5xlc

View 5xlc on RCSB PDB site
Description: The structure of hemagglutinin Q226L-G228S mutant from an avian-origin H4N6 influenza virus in complex with avian receptor analog LSTa
Class: viral protein
Keywords: H4 hemagglutinin, influenza virus, receptor binding, VIRAL PROTEIN
Deposited on 2017-05-10, released 2017-08-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-08-02, with a file datestamp of 2017-07-28.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hemagglutinin
    Species: Influenza A virus (strain A/Duck/Czechoslovakia/1956 H4N6) [TaxId:385590]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot A3KF09
      • engineered mutation (222)
      • engineered mutation (224)
    Domains in SCOPe 2.06: d5xlca_
  • Chain 'B':
    Compound: Hemagglutinin
    Species: Influenza A virus (strain A/Duck/Czechoslovakia/1956 H4N6) [TaxId:385590]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot A3KF09
      • engineered mutation (222)
      • engineered mutation (224)
    Domains in SCOPe 2.06: d5xlcb_
  • Chain 'C':
    Compound: Hemagglutinin
    Species: Influenza A virus (strain A/Duck/Czechoslovakia/1956 H4N6) [TaxId:385590]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5xlcc_
  • Chain 'D':
    Compound: Hemagglutinin
    Species: Influenza A virus (strain A/Duck/Czechoslovakia/1956 H4N6) [TaxId:385590]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5xlcd_
  • Heterogens: NAG, SIA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5xlcA (A:)
qnytgnpvicmghhavangtmvktladdqvevvtaqelvesqnlpelcpsplrlvdgqtc
diingalgspgcdhlngaewdvfierpnavdtcypfdvpeyqslrsilanngkfefiaee
fqwntvkqngksgackranvndffnrlnwlvksdgnayplqnltkinngdyarlyiwgvh
hpstdteqtnlyknnpggvtvstktsqtsvvpnigsrplvrglssrvsfywtivepgdli
vfntignliaprghyklnnqkkstilntaipigscvskchtdkgslsttkpfqnisriav
gdcpryvkqgslklatgmrnipekasr

    Sequence, based on observed residues (ATOM records): (download) 
    >5xlcA (A:)
gnpvicmghhavangtmvktladdqvevvtaqelvesqnlpelcpsplrlvdgqtcdiin
galgspgcdhlngaewdvfierpnavdtcypfdvpeyqslrsilanngkfefiaeefqwn
tvkqngksgackranvndffnrlnwlvksdgnayplqnltkinngdyarlyiwgvhhpst
dteqtnlyknnpggvtvstktsqtsvvpnigsrplvrglssrvsfywtivepgdlivfnt
ignliaprghyklnnqkkstilntaipigscvskchtdkgslsttkpfqnisriavgdcp
ryvkqgslklatgmrnipe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5xlcB (B:)
qnytgnpvicmghhavangtmvktladdqvevvtaqelvesqnlpelcpsplrlvdgqtc
diingalgspgcdhlngaewdvfierpnavdtcypfdvpeyqslrsilanngkfefiaee
fqwntvkqngksgackranvndffnrlnwlvksdgnayplqnltkinngdyarlyiwgvh
hpstdteqtnlyknnpggvtvstktsqtsvvpnigsrplvrglssrvsfywtivepgdli
vfntignliaprghyklnnqkkstilntaipigscvskchtdkgslsttkpfqnisriav
gdcpryvkqgslklatgmrnipekasr

    Sequence, based on observed residues (ATOM records): (download) 
    >5xlcB (B:)
gnpvicmghhavangtmvktladdqvevvtaqelvesqnlpelcpsplrlvdgqtcdiin
galgspgcdhlngaewdvfierpnavdtcypfdvpeyqslrsilanngkfefiaeefqwn
tvkqngksgackranvndffnrlnwlvksdgnayplqnltkinngdyarlyiwgvhhpst
dteqtnlyknnpggvtvstktsqtsvvpnigsrplvrglssrvsfywtivepgdlivfnt
ignliaprghyklnnqkkstilntaipigscvskchtdkgslsttkpfqnisriavgdcp
ryvkqgslklatgmrnipe

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5xlcC (C:)
glfgaiagfiengwqglidgwygfrhqnaegtgtaadlkstqaaidqingklnrliektn
dkyhqiekefeqvegriqdlekyvedtkidlwsynaellvalenqhtidvtdsemnklfe
rvrrqlrenaedkgngcfeifhkcdnnciesirngtydhdiyrdeainnrfqiqgv

    Sequence, based on observed residues (ATOM records): (download) 
    >5xlcC (C:)
glfgaiagfiengwqglidgwygfrhqnaegtgtaadlkstqaaidqingklnrliektn
dkyhqiekefeqvegriqdlekyvedtkidlwsynaellvalenqhtidvtdsemnklfe
rvrrqlrenaedkgngcfeifhkcdnnciesirngtydhdiyrdeainnrfq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5xlcD (D:)
glfgaiagfiengwqglidgwygfrhqnaegtgtaadlkstqaaidqingklnrliektn
dkyhqiekefeqvegriqdlekyvedtkidlwsynaellvalenqhtidvtdsemnklfe
rvrrqlrenaedkgngcfeifhkcdnnciesirngtydhdiyrdeainnrfqiqgv

    Sequence, based on observed residues (ATOM records): (download) 
    >5xlcD (D:)
glfgaiagfiengwqglidgwygfrhqnaegtgtaadlkstqaaidqingklnrliektn
dkyhqiekefeqvegriqdlekyvedtkidlwsynaellvalenqhtidvtdsemnklfe
rvrrqlrenaedkgngcfeifhkcdnnciesirngtydhdiyrdeainnrfq