PDB entry 5l03

View 5l03 on RCSB PDB site
Description: Crystal structure of 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE Synthase from BURKHOLDERIA PSEUDOMALLEI bound to L-tryptophan hydroxamate
Class: lyase
Keywords: MEP Pathway, IspF, Inhibitor, Complex, LYASE
Deposited on 2016-07-26, released 2017-11-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 1.47 Å
R-factor: N/A
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Burkholderia pseudomallei [TaxId:28450]
    Gene: ispF, DP46_3085, ERS012314_03919, SY87_14040
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5l03a_
  • Chain 'B':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Burkholderia pseudomallei [TaxId:28450]
    Gene: ispF, DP46_3085, ERS012314_03919, SY87_14040
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5l03b_
  • Chain 'C':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Burkholderia pseudomallei [TaxId:28450]
    Gene: ispF, DP46_3085, ERS012314_03919, SY87_14040
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5l03c_
  • Heterogens: ZN, 6ZB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5l03A (A:)
mdfrigqgydvhqlvpgrpliiggvtipyergllghsdadvllhaitdalfgaaalgdig
rhfsdtdprfkgadsrallrecasrvaqagfairnvdstiiaqapklaphidamraniaa
dldlpldrvnvkaktneklgylgrgegieaqaaalvvr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5l03B (B:)
mdfrigqgydvhqlvpgrpliiggvtipyergllghsdadvllhaitdalfgaaalgdig
rhfsdtdprfkgadsrallrecasrvaqagfairnvdstiiaqapklaphidamraniaa
dldlpldrvnvkaktneklgylgrgegieaqaaalvvr

    Sequence, based on observed residues (ATOM records): (download) 
    >5l03B (B:)
mdfrigqgydvhqlvpgrpliiggvtipyerglladvllhaitdalfgaaalgdigrhfd
srallrecasrvaqagfairnvdstiiaqapklaphidamraniaadldlpldrvnvkak
tneklgylgrgegieaqaaalvvr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5l03C (C:)
mdfrigqgydvhqlvpgrpliiggvtipyergllghsdadvllhaitdalfgaaalgdig
rhfsdtdprfkgadsrallrecasrvaqagfairnvdstiiaqapklaphidamraniaa
dldlpldrvnvkaktneklgylgrgegieaqaaalvvr

    Sequence, based on observed residues (ATOM records): (download) 
    >5l03C (C:)
mdfrigqgydvhqlvpgrpliiggvtipyergllghsdadvllhaitdalfgaaalgdig
rhfdsrallrecasrvaqagfairnvdstiiaqapklaphidamraniaadldlpldrvn
vkaktneklgylgrgegieaqaaalvvr