PDB entry 5j28

View 5j28 on RCSB PDB site
Description: Ki67-PP1g (protein phosphatase 1, gamma isoform) holoenzyme complex
Class: hydrolase/protein binding
Keywords: PP1 gamma; RepoMan, Ki-67; Phosphatase, HYDROLASE-PROTEIN BINDING complex
Deposited on 2016-03-29, released 2016-10-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-27, with a file datestamp of 2017-09-22.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: Ppp1cc
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5j28a_
  • Chain 'B':
    Compound: Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: Ppp1cc
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5j28b_
  • Chain 'C':
    Compound: Antigen Ki-67
    Species: Homo sapiens [TaxId:9606]
    Gene: MKI67
    Database cross-references and differences (RAF-indexed):
    • Uniprot P46013
      • engineered mutation (34)
  • Chain 'D':
    Compound: Antigen Ki-67
    Species: Homo sapiens [TaxId:9606]
    Gene: MKI67
    Database cross-references and differences (RAF-indexed):
    • Uniprot P46013
      • engineered mutation (34)
  • Heterogens: MLI, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5j28A (A:)
ghmlnidsiiqrllevrgskpgknvqlqeneirglclksreiflsqpilleleaplkicg
dihgqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffllrg
nhecasinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlqsm
eqirrimrptdvpdqgllcdllwsdpdkdvlgwgendrgvsftfgaevvakflhkhdldl
icrahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpaekkk
pnatr

    Sequence, based on observed residues (ATOM records): (download) 
    >5j28A (A:)
lnidsiiqrllevrgskpgknvqlqeneirglclksreiflsqpilleleaplkicgdih
gqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffllrgnhe
casinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlqsmeqi
rrimrptdvpdqgllcdllwsdpdkdvlgwgendrgvsftfgaevvakflhkhdldlicr
ahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5j28B (B:)
ghmlnidsiiqrllevrgskpgknvqlqeneirglclksreiflsqpilleleaplkicg
dihgqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffllrg
nhecasinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlqsm
eqirrimrptdvpdqgllcdllwsdpdkdvlgwgendrgvsftfgaevvakflhkhdldl
icrahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpaekkk
pnatr

    Sequence, based on observed residues (ATOM records): (download) 
    >5j28B (B:)
lnidsiiqrllevrgskpgknvqlqeneirglclksreiflsqpilleleaplkicgdih
gqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffllrgnhe
casinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlqsmeqi
rrimrptdvpdqgllcdllwsdpdkdvlgwgendrgvsftfgaevvakflhkhdldlicr
ahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpa

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.