PDB entry 4yp6

View 4yp6 on RCSB PDB site
Description: Crystal structure of Methanobacterium thermoautotrophicum NMNAT in complex with NADP
Class: transferase
Keywords: inhibitor, TRANSFERASE
Deposited on 2015-03-12, released 2015-10-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-10-14, with a file datestamp of 2015-10-09.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nicotinamide-nucleotide Adenylyltransferase
    Species: Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) [TaxId:187420]
    Gene: MTH_150
    Database cross-references and differences (RAF-indexed):
    • Uniprot O26253 (3-End)
      • expression tag (2)
      • engineered mutation (10)
    Domains in SCOPe 2.07: d4yp6a1, d4yp6a2
  • Chain 'B':
    Compound: Nicotinamide-nucleotide Adenylyltransferase
    Species: Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) [TaxId:187420]
    Gene: MTH_150
    Database cross-references and differences (RAF-indexed):
    • Uniprot O26253 (3-End)
      • expression tag (2)
      • engineered mutation (10)
    Domains in SCOPe 2.07: d4yp6b1, d4yp6b2
  • Chain 'C':
    Compound: Nicotinamide-nucleotide Adenylyltransferase
    Species: Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) [TaxId:187420]
    Gene: MTH_150
    Database cross-references and differences (RAF-indexed):
    • Uniprot O26253 (3-End)
      • expression tag (2)
      • engineered mutation (10)
    Domains in SCOPe 2.07: d4yp6c1, d4yp6c2
  • Heterogens: NAP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4yp6A (A:)
vmtmrgllvgkmqpfhrghlqviksileevdeliicigsaqlshsirdpftagervmmlt
kalsengipasryyiipvqdiecnalwvghikmltppfdrvysgnplvqrlfsedgyevt
applfyrdrysgtevrrrmlddgdwrsllpesvvevideingverikhlakkevselggi
s

    Sequence, based on observed residues (ATOM records): (download) 
    >4yp6A (A:)
tmrgllvgkmqpfhrghlqviksileevdeliicigsaqlshsirdpftagervmmltka
lsengipasryyiipvqdiecnalwvghikmltppfdrvysgnplvqrlfsedgyevtap
plfyrdrysgtevrrrmlddgdwrsllpesvvevideingverikhlak

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4yp6B (B:)
vmtmrgllvgkmqpfhrghlqviksileevdeliicigsaqlshsirdpftagervmmlt
kalsengipasryyiipvqdiecnalwvghikmltppfdrvysgnplvqrlfsedgyevt
applfyrdrysgtevrrrmlddgdwrsllpesvvevideingverikhlakkevselggi
s

    Sequence, based on observed residues (ATOM records): (download) 
    >4yp6B (B:)
tmrgllvgkmqpfhrghlqviksileevdeliicigsaqlshsirdpftagervmmltka
lsengipasryyiipvqdiecnalwvghikmltppfdrvysgnplvqrlfsedgyevtap
plfyrdrysgtevrrrmlddgdwrsllpesvvevideingverikhlak

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4yp6C (C:)
vmtmrgllvgkmqpfhrghlqviksileevdeliicigsaqlshsirdpftagervmmlt
kalsengipasryyiipvqdiecnalwvghikmltppfdrvysgnplvqrlfsedgyevt
applfyrdrysgtevrrrmlddgdwrsllpesvvevideingverikhlakkevselggi
s

    Sequence, based on observed residues (ATOM records): (download) 
    >4yp6C (C:)
tmrgllvgkmqpfhrghlqviksileevdeliicigsaqlshsirdpftagervmmltka
lsengipasryyiipvqdiecnalwvghikmltppfdrvysgnplvqrlfsedgyevtap
plfyrdrysgtevrrrmlddgdwrsllpesvvevideingverikhlak