PDB entry 4yoi

View 4yoi on RCSB PDB site
Description: Structure of HKU4 3CLpro bound to non-covalent inhibitor 1A
Class: Hydrolase/Hydrolase Inhibitor
Keywords: HKU4 3CLpro Mpro nsp5, Hydrolase-Hydrolase Inhibitor complex
Deposited on 2015-03-11, released 2015-08-05
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-09-09, with a file datestamp of 2015-09-04.
Experiment type: XRAY
Resolution: 1.82 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3C-like proteinase
    Species: Bat coronavirus HKU4 [TaxId:694007]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4yoia_
  • Chain 'B':
    Compound: 3C-like proteinase
    Species: Bat coronavirus HKU4 [TaxId:694007]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4yoib_
  • Heterogens: 4F4, ACT, FMT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4yoiA (A:)
sglvkmsapsgavencivqvtcgsmtlnglwldntvwcprhimcpadqltdpnydallis
ktnhsfivqkhigaqanlrvvahsmvgvllkltvdvanpstpaytfstvkpgasfsvlac
yngkptgvftvnlrhnstikgsflcgscgsvgytenggvinfvymhqmelsngthtgssf
dgvmygafedkqthqlqltdkyctinvvawlyaavlngckwfvkptrvgivtynewalsn
qftefvgtqsidmlahrtgvsveqmlaaiqslhagfqgktilgqstledeftpddvnmqv
mgvvmq

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4yoiB (B:)
sglvkmsapsgavencivqvtcgsmtlnglwldntvwcprhimcpadqltdpnydallis
ktnhsfivqkhigaqanlrvvahsmvgvllkltvdvanpstpaytfstvkpgasfsvlac
yngkptgvftvnlrhnstikgsflcgscgsvgytenggvinfvymhqmelsngthtgssf
dgvmygafedkqthqlqltdkyctinvvawlyaavlngckwfvkptrvgivtynewalsn
qftefvgtqsidmlahrtgvsveqmlaaiqslhagfqgktilgqstledeftpddvnmqv
mgvvmq